Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1172955 | 0.89 | MAPT (0.33) | SMN1; SMN2MAPTLIN28ATDP1L3MBTL1 | |
| SCHEMBL29725206 | 0.82 | — | — | |
| SCHEMBL485115 | 0.82 | — | — | |
| SCHEMBL29415695 | 0.80 | — | — | |
| SCHEMBL6563 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL243023 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL29994471 | 0.78 | — | — | |
| Iodide SCHEMBL6246153 | 0.78 | — | — | |
| Bromide SCHEMBL29427044 | 0.78 | — | — | |
| Bromide SCHEMBL119703 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838536-B2 | Water-soluble zinc ionophores, zinc chelators, and/or zinc complexes and use for treating cancer | Sessler, Jonathan L. (US) | 2010-11-23 | — | — | US | disclosed |
| US-20090209509-A1 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | Sessler, Jonathan L. (US) | 2009-08-20 | — | — | US | disclosed |
| US-7528125-B2 | Water-soluble zinc ionophores, zinc chelators, and/or zinc complexes and use for treating cancer | Sessler, Jonathan L. (US) | 2009-05-05 | — | — | US | disclosed |
| US-20070219276-A1 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | PHARMACYCLICS, INC (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219276-A1 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | SLC39A11, SLC39A3, SLC30A6 | SMN1; SMN2 1995/4885MAPT 4379/4885LIN28A 2375/4885 |
| US-20090209509-A1 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER | SLC39A11, SLC39A3, SLC30A6 | SMN1; SMN2 1995/4885MAPT 4379/4885LIN28A 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.