Pyrrolidine

Pyrrolidine

SCHEMBL3748939

C1CCNC1.[LiH]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467586 0.95
Piperidine SCHEMBL2235377 0.95
Azepane SCHEMBL1796962 0.95
Azacyclotridecane SCHEMBL22607619 0.95 ALDH1A1 (0.90)
SCHEMBL28373479 0.95 ALDH1A1 (0.90)
SCHEMBL3811182 0.94 ALDH1A1 (0.89)
SCHEMBL576640 0.94 ALDH1A1 (0.89)
Pyrrolidine SCHEMBL11288790 0.94
Pyrrolidine SCHEMBL7827746 0.94 ALDH1A1 (0.89)
Pyrrolidine SCHEMBL148449 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903175-A Synthesis method and application of lithium pyrrolidine 浙江江北药业有限公司 2024-04-19 CN claimed
EP-3717890-B1 OLEFIN OLIGOMERIZATION METHOD USING ONLINE MEASUREMENT OF CHROMIUM CONCENTRATION IN A CATALYTIC SYSTEM SIBUR HOLDING PUBLIC JOINT STOCK CO (RU) 2024-02-28 EP claimed
CN-114591441-B Recombinant TET enzyme MBD3-NgTET1 and application thereof in improving 5caC (cubic-alternating current) ratio in TET enzyme oxidation product 翌圣生物科技(上海)股份有限公司 2023-06-20 CN claimed
CN-114899513-A Formation method of aluminum plastic film soft-package lithium iron phosphate battery 天能新能源(湖州)有限公司 2022-08-12 CN claimed
CN-114421008-A Wettability-enhanced lithium ion battery electrolyte and application thereof 陕西泽邦环境科技有限公司 2022-04-29 CN claimed
CN-114421009-A Long-life lithium ion battery electrolyte and application thereof 陕西泽邦环境科技有限公司 2022-04-29 CN claimed
CN-111620903-A C-nucleoside analogue, preparation method and application of nitrile-containing C-nucleoside compound for synthesizing Rudexilvir 安徽贝克联合制药有限公司 2020-09-04 CN claimed
CN-107863516-B Nitrogen-containing nano lithium titanate composite material, preparation method thereof and lithium ion battery 洛阳月星新能源科技有限公司 2020-07-28 CN claimed
CN-109790237-A Catalyst system for olefin oligomerization and the method for olefin oligomerization 公共型股份公司希布尔控股 2019-05-21 CN claimed
CN-105392737-B Stabilized lithium metal structures coated with nitrogen-containing shells and methods of making the same 罗克伍德锂有限责任公司 2018-05-18 CN claimed
US-20030187164-A1 Solutions of lithium pyrrolidine in tetrahydrofuran (thf)/hydrocarbons CHEMETALL GMBH (DE) 2003-10-02 US claimed
EP-1292599-A1 SOLUTIONS OF LITHIUM PYRROLIDINE IN TETRAHYDROFURAN (THF)/HYDROCARBONS Chemetall GmbH (DE) 2003-03-19 EP claimed
US-6506929-B1 Selectively reducing carbonyl function of lactone moiety of lovastatin to hemiacetal, methylating with strong base and methyl iodide in inert solvent, oxidizing product to give simvastatin APOTEX INC. (CA) 2003-01-14 US claimed
US-6472542-B1 DECYCLIZATION, AMIDATION, SILATION PROTECTING HYDROXYLS WITH HEXAMETHYIDISILAZANE, METHYLATION, HYDROLYSIS OF AMIDE AND SILANOLS, AMMONIATION, LACTONATION AND RECRYSTALLIZATION; HIGH YIELD AND PURITY FERMIC S.A. DE C.V. (MX) 2002-10-29 US claimed
EP-1087958-B1 PROCESS TO MANUFACTURE SIMVASTATIN AND INTERMEDIATES APOTEX INC (CA) 2002-09-04 EP claimed
WO-2001094354-A1 SOLUTIONS OF LITHIUM PYRROLIDINE IN TETRAHYDROFURAN (THF)/HYDROCARBONS CHEMETALL GMBH (DE) 2001-12-13 WO claimed
EP-1087958-A1 PROCESS TO MANUFACTURE SIMVASTATIN AND INTERMEDIATES APOTEX INC. (CA) 2001-04-04 EP claimed
WO-1999065892-A1 PROCESS TO MANUFACTURE SIMVASTATIN AND INTERMEDIATES APOTEX INC. (CA) 1999-12-23 WO claimed
CN-1188763-A Process for manufacturing simvastatin from lovastatin or mevinolinic acid RANBAXY LAB LTD (IN) 1998-07-29 CN claimed
EP-0299656-B1 PROCESS FOR ALPHA-C-ALKYLATION OF THE 8-ACYL GROUP OF MEVINOLIN AND ANALOGS THEREOF MERCK & CO. INC. (US) 1990-12-12 EP claimed