Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.68 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.56 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.56 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967879 | 0.87 | BCL9 (0.70) | BCL9CTNNB1GAAPTPN7PTPN12 | |
| SCHEMBL957930 | 0.87 | BCL9 (0.81) | BCL9CTNNB1GAAPTPN7PTPN12 | |
| SCHEMBL13892906 | 0.86 | BCL9 (0.64) | BCL9CTNNB1GAAPTPN7PTPN12 | |
| SCHEMBL2607873 | 0.86 | BCL9 (0.73) | BCL9CTNNB1GAAPTPN7PTPN12 | |
| SCHEMBL11718045 | 0.85 | BCL9 (0.68) | BCL9CTNNB1GAAPTPN7PTPN12 | |
| SCHEMBL15604041 | 0.84 | BCL9 (0.54) | BCL9CTNNB1GAAPTPN7PTPN12 | |
| SCHEMBL2294260 | 0.84 | BCL9 (0.66) | BCL9CTNNB1GAAPTPN7PTPN12 | |
| SCHEMBL2294100 | 0.84 | BCL9 (0.76) | BCL9CTNNB1GAAPTPN7PTPN12 | |
| SCHEMBL4076398 | 0.84 | BCL9 (0.66) | BCL9CTNNB1GAAPTPN7PTPN12 | |
| SCHEMBL531007 | 0.84 | BCL9 (0.76) | BCL9CTNNB1GAAPTPN7PTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102455-A | HYDROPHILIC SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF | DONG A ST CO LTD | 2015-11-25 | — | — | CN | disclosed |
| US-20100297456-A1 | Diamine, Polyamic Acid and Polyimide | RICOH COMPANY, LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
| US-4052212-A | ETHER-ESTER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297456-A1 | Diamine, Polyamic Acid and Polyimide | PARN, PUF60, PARG | BCL9 2790/4885CTNNB1 4857/4885GAA 2011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.