Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.70 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.57 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.57 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MYOC | Q99972 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12857961 | 0.92 | BCL9 (0.65) | BCL9CTNNB1GAAKMT2AMAPT | |
| SCHEMBL18281479 | 0.91 | BCL9 (0.64) | BCL9CTNNB1GAAKMT2AMAPT | |
| SCHEMBL13320022 | 0.91 | BCL9 (0.64) | BCL9CTNNB1GAAKMT2AMAPT | |
| SCHEMBL5370222 | 0.90 | BCL9 (0.67) | BCL9CTNNB1GAAKMT2AMAPT | |
| SCHEMBL10016250 | 0.89 | BCL9 (0.57) | BCL9CTNNB1GAAKMT2AMAPT | |
| SCHEMBL957930 | 0.89 | BCL9 (0.81) | BCL9CTNNB1GAAKMT2AMAPT | |
| SCHEMBL13477957 | 0.88 | BCL9 (0.60) | BCL9CTNNB1GAAKMT2AMAPT | |
| SCHEMBL17085310 | 0.87 | BCL9 (0.56) | BCL9CTNNB1GAAKMT2AMAPT | |
| SCHEMBL11718045 | 0.87 | BCL9 (0.68) | BCL9CTNNB1GAAKMT2AMAPT | |
| SCHEMBL3749119 | 0.87 | BCL9 (0.68) | BCL9CTNNB1GAAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362388-A1 | Disulfide Polymers and Methods of Use | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2017-12-21 | — | — | US | disclosed |
| US-9056155-B1 | Coatings having an elastic primer layer | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2015-06-16 | — | — | US | disclosed |
| US-8968716-B2 | In situ-forming hydrogel for tissue adhesives and biomedical use thereof | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-03-03 | — | — | US | disclosed |
| US-8815277-B2 | In situ forming hydrogel and biomedical use thereof | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2014-08-26 | — | — | US | disclosed |
| US-8389044-B2 | Poly(ester amide)-based drug delivery systems with controlled release rate and morphology | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-8377107-B2 | Poly(ester amide)-based drug delivery systems with controlled release rate and morphology | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2013-02-19 | — | — | US | disclosed |
| US-8377499-B2 | Methods of forming Poly(ester amide)-based drug delivery systems with controlled release rate and morphology | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120156164-A1 | IN SITU-FORMING HYDROGEL FOR TISSUE ADHESIVES AND BIOMEDICAL USE THEREOF | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2012-06-21 | — | — | US | disclosed |
| US-20120100103-A1 | IN SITU FORMING HYDROGEL AND BIOMEDICAL USE THEREOF | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2012-04-26 | — | — | US | disclosed |
| US-20110200660-A1 | POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| US-20080175886-A1 | Blends Of Poly(Ester Amide) Polymers | ADVANCED CARDIOVASCULAR SYSTEM INC. (US) | 2008-07-24 | — | — | US | disclosed |
| US-20080177008-A1 | Blends Of Poly(Ester Amide) Polymers | ADVANCED CARDIOVASCULAR SYSTEMS INC. (US) | 2008-07-24 | — | — | US | disclosed |
| US-20080167712-A1 | POLY(ESTER AMIDE) FILLER BLENDS FOR MODULATION OF COATING PROPERTIES | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2008-07-10 | — | — | US | disclosed |
| US-7390497-B2 | Poly(ester amide) filler blends for modulation of coating properties | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2008-06-24 | — | — | US | disclosed |
| US-7365133-B2 | Blends of poly(ester amide) polymers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-20080095918-A1 | Coating construct with enhanced interfacial compatibility | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2008-04-24 | — | — | US | disclosed |
| US-20070202147-A1 | Poly(ester amide)-based drug delivery systems with controlled release rate and morphology | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2007-08-30 | — | — | US | disclosed |
| US-20070135909-A1 | Adhesion polymers to improve stent retention | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070093617-A1 | Blends of poly(ester amide) polymers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2007-04-26 | — | — | US | disclosed |
| US-7166680-B2 | Blends of poly(ester amide) polymers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2007-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100103-A1 | IN SITU FORMING HYDROGEL AND BIOMEDICAL USE THEREOF | CD44, MYB, PLOD3 | BCL9 4543/4885CTNNB1 3154/4885GAA 1945/4885 |
| US-20170362388-A1 | Disulfide Polymers and Methods of Use | MPST, P4HB, PDIA5 | BCL9 1736/4885CTNNB1 4741/4885GAA 1172/4885 |
| US-20110200660-A1 | POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY | PAM, PUF60, ACMSD | BCL9 3968/4885CTNNB1 4885/4885GAA 296/4885 |
| US-20080177008-A1 | Blends Of Poly(Ester Amide) Polymers | TAAR5, TAAR1, PAM | BCL9 102/4885CTNNB1 891/4885GAA 826/4885 |
| US-20080175886-A1 | Blends Of Poly(Ester Amide) Polymers | BMP2, NAAA, PHOSPHO1 | BCL9 951/4885CTNNB1 2152/4885GAA 682/4885 |
| US-20070202147-A1 | Poly(ester amide)-based drug delivery systems with controlled release rate and morphology | PUF60, PAM, ACMSD | BCL9 4046/4885CTNNB1 4885/4885GAA 385/4885 |
| US-20120156164-A1 | IN SITU-FORMING HYDROGEL FOR TISSUE ADHESIVES AND BIOMEDICAL USE THEREOF | CD44, DBH, TYR | BCL9 2547/4885CTNNB1 3244/4885GAA 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.