SCHEMBL3749152

SCHEMBL3749152

O=C[C@H](O)C(O)(O)[C@H](O)[C@H](O)CO

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.39
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28258836 1.00 AKR1B1 (0.39) AKR1B1LMNAL3MBTL1TDP1
SCHEMBL3239490 0.80 AKR1B1 (0.37) AKR1B1LMNAL3MBTL1
SCHEMBL680091 0.80 AKR1B1 (0.37) AKR1B1LMNAL3MBTL1
SCHEMBL26929232 0.80 AKR1B1 (0.37) AKR1B1LMNAL3MBTL1
SCHEMBL7641965 0.80 AKR1B1 (0.37) AKR1B1LMNAL3MBTL1
SCHEMBL2635171 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL458624 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL10713443 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL8857027 0.78 AKR1B1 (0.36) AKR1B1
SCHEMBL309710 0.78 AKR1B1 (0.36) AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11851455-B2 Acidic dystroglycan oligosaccharide compound and method for making same UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2023-12-26 US disclosed
EP-4289958-A1 PROTEIN HAVING 1,3-FUCOSYLTRANSFERASE ACTIVITY, AND METHOD FOR PRODUCING FUCOSE-CONTAINING SUGAR Kyowa Hakko Bio Co., Ltd. (JP) 2023-12-13 EP disclosed
CN-116806260-A Method for producing protein having 1, 3-fucosyltransferase activity and fucose-containing saccharide 协和发酵生化株式会社 2023-09-26 CN disclosed
WO-2019136399-A1 ACIDIC DYSTROGLYCAN OLIGOSACCHARIDE COMPOUND AND METHOD FOR MAKING SAME UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2019-07-11 WO disclosed
WO-2012067614-A1 PERIODONTITIS TREATMENT KADOR PETER F (US) 2012-05-24 WO disclosed
WO-2012067614-A1 PERIODONTITIS TREATMENT KADOR PETER F (US) 2012-05-24 WO disclosed
US-20100292287-A1 Periodontitis treatment KADOR PETER F 2010-11-18 US disclosed
US-20100292287-A1 Periodontitis treatment KADOR PETER F 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851455-B2 Acidic dystroglycan oligosaccharide compound and method for making same OGA, CSGALNACT1, B3GAT3 AKR1B1 3930/4885LMNA 844/4885L3MBTL1 1219/4885
US-20100292287-A1 Periodontitis treatment LCT, NNT, APRT AKR1B1 15/4885LMNA 3492/4885L3MBTL1 974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.