Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3749159 | 1.00 | CYP19A1 (0.62) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL13046036 | 1.00 | CYP19A1 (0.62) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL13046032 | 0.91 | CYP19A1 (0.72) | CYP19A1CYP3A4 | |
| SCHEMBL3744536 | 0.91 | CYP19A1 (0.72) | CYP19A1CYP3A4 | |
| SCHEMBL10407031 | 0.84 | SERPINA6 (0.76) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL3742147 | 0.82 | CYP19A1 (0.52) | CYP19A1CYP3A4 | |
| SCHEMBL3744658 | 0.82 | CYP19A1 (0.52) | CYP19A1CYP3A4 | |
| SCHEMBL3742150 | 0.81 | CYP19A1 (0.51) | CYP19A1CYP3A4 | |
| SCHEMBL3744602 | 0.80 | CYP19A1 (0.54) | CYP19A1 | |
| SCHEMBL3744597 | 0.80 | CYP19A1 (0.54) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292184-A1 | 17BETA-CYANO-19-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | BAYER SCHERING PHARMA AG (DE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292184-A1 | 17BETA-CYANO-19-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | HSD17B11, HSD17B7, NR5A1 | CYP19A1 14/4885CYP3A4 166/4885SHBG 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.