Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760237 | 0.85 | KCNA5 (0.58) | GAATSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3750215 | 0.83 | GAA (0.90) | GAATSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3758249 | 0.82 | GAA (0.78) | GAATSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3757558 | 0.81 | GAA (0.72) | GAATSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3942742 | 0.80 | GAA (0.78) | GAATSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3747913 | 0.80 | GAA (0.85) | GAATSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL27755672 | 0.80 | TSHR (0.73) | GAATSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL27755671 | 0.79 | TSHR (0.69) | GAATSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3748963 | 0.79 | GAA (0.76) | GAATSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3756564 | 0.76 | TP53 (0.77) | GAATSHRALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298392-A1 | Isoindoline Derivatives For The Treatment Of Arrhythmias | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298392-A1 | Isoindoline Derivatives For The Treatment Of Arrhythmias | KCNH1, KCNH2, KCNQ2 | GAA 4674/4885TSHR 1483/4885ALDH1A1 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.