Oxidopamine

Oxidopamine

SCHEMBL37507

NCCc1cc(O)c(O)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 4/20 1.00
TDP1 Q9NUW8 4/20 1.00
MEN1 O00255 2/20 1.00
RAD52 P43351 2/20 1.00
KMT2A Q03164 2/20 1.00
APEX1 P27695 2/20 1.00
BLM P54132 2/20 1.00
GAPDH P04406 1/20 1.00
THRB P10828 1/20 1.00
KDM4E B2RXH2 3/20 0.95
MAPT P10636 3/20 0.95
MAPK1 P28482 3/20 0.95
ALOX15 P16050 2/20 0.95
HSD17B10 Q99714 2/20 0.95
AGO2 Q9UKV8 1/20 0.95
TAAR1 Q96RJ0 3/20 0.50
ADRA2A P08913 2/20 0.48
DRD2 P14416 2/20 0.48
DRD1 P21728 2/20 0.48
DRD4 P21917 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxidopamine SCHEMBL29367988 1.00 RECQL (1.00) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL30862335 0.97 RECQL (1.00) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL718426 0.97 RECQL (1.00) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL29419900 0.97 RECQL (0.95) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL738049 0.97 RECQL (0.95) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL20398182 0.95 RECQL (0.91) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL12557128 0.85 RECQL (0.74) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL1110886 0.85 RECQL (0.74) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL14452263 0.81 MEN1 (0.68) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL20409280 0.81 MEN1 (0.68) RECQLTDP1MEN1RAD52KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8412 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4713433-A2 LIVER ORGANOIDS WITH INTRAHEPATIC SYMPATHETIC NERVES, AND METHODS OF USE THEREOF Children's Hospital Medical Center (US) 2026-03-25 EP claimed
EP-4649090-A1 ANTI-UNC5C ANTIBODIES ELI LILLY AND COMPANY (US) 2025-11-19 EP claimed
EP-3911795-B1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2025-10-01 EP claimed
US-20250172542-A1 METHOD FOR INDUCING ARTIFICIAL AGEING IN A STEM CELL AND USES OF SAID CELL CLOCK BIO LIMITED (GB) 2025-05-29 US claimed
CN-119949276-A Parkinson's disease rat model based on brain microcirculation disturbance and construction method and application thereof 北京大学人民医院 2025-05-09 CN claimed
CN-119950710-A Piezoelectric nano-particle BTNP-pDA, preparation method thereof and application thereof in parkinsonism research 青岛大学 2025-05-09 CN claimed
CN-119923462-A Method for inducing artificial ageing in stem cells and use of said cells 时钟生物有限公司 2025-05-02 CN claimed
WO-2025078659-A1 METHOD AND KIT FOR INDUCING CELL DIFFERENTIATION, AND REGULATED NECROTIC CELL DEATH INHIBITOR FOR USE FOR REGENERATING DAMAGED TISSUES SEABELIFE (FR) 2025-04-17 WO claimed
CN-116516690-B Fiber impregnating solution for improving bonding effect between nylon fiber and rubber and preparation method thereof 青岛科技大学 2025-03-28 CN claimed
WO-2003001197-A1 ASSAY FOR TOXIN INDUCED NEURONAL DEGENERATION AND VIABILITY IN C. ELEGANS VANDERBILT UNIVERSITY (US) 2003-01-03 WO claimed
EP-1242817-A2 METHOD FOR ESTABLISHING NEUROLOGICALLY RELEVANT PROPERTIES OF A MATERIAL Elegene AG (DE) 2002-09-25 EP claimed
WO-2002043559-A2 METHODS AND KITS FOR DIAGNOSIS OF SCHIZOPHRENIA RAMBAM MEDICAL CENTER FUNDS FOR MEDICAL RESEARCH DEVELOPMENT OF INFRASTRUCTURE AND HEALTH SERVICES (IL) 2002-06-06 WO claimed
WO-2001046690-A2 METHOD FOR ESTABLISHING NEUROLOGICALLY RELEVANT PROPERTIES OF A MATERIAL AVENTIS PHARMA DEUTSCHLANDD GMBH (DE) 2001-06-28 WO claimed
EP-0672148-A1 METHOD FOR MAKING STABLE, EXTRACELLULAR TYROSINASE AND SYNTHESIS OF POLYPHENOLIC POLYMERS THEREFROM Biosource Technologies, Inc. (US) 1995-09-20 EP claimed
US-5340734-A In vitro biosynthesis the melanins in presence of a substrate consisting of tyrosine binding single amino acid, a dipeptide or an oligopeptide BIOSOURCE GENETICS CORPORATION (US) 1994-08-23 US claimed
WO-1994012644-A2 METHOD FOR MAKING STABLE, EXTRACELLULAR TYROSINASE AND SYNTHESIS OF POLYPHENOLIC POLYMERS THEREFROM BIOSOURCE GENETICS CORPORATION (US) 1994-06-09 WO claimed
US-5279543-A Device for iontophoretic non-invasive sampling or delivery of substances THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-01-18 US claimed
US-5147294-A Therapeutic method for reducing chronic pain in a living subject TRUSTEES OF BOSTON UNIVERSITY (US) 1992-09-15 US claimed
US-3993436-A Dyeing live hair with melanin precursors SHISEIDO CO., LTD. (JA) 1976-11-23 US claimed