Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Oxidopamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.46 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.46 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.46 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D known ✓ | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B known ✓ | P35368 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 4/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.95 |
| ▸ | MEN1 | O00255 | 2/20 | 0.95 |
| ▸ | RAD52 | P43351 | 2/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.95 |
| ▸ | APEX1 | P27695 | 2/20 | 0.95 |
| ▸ | BLM | P54132 | 2/20 | 0.95 |
| ▸ | GAPDH | P04406 | 1/20 | 0.95 |
| ▸ | THRB | P10828 | 1/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.91 |
| ▸ | MAPT | P10636 | 3/20 | 0.91 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxidopamine SCHEMBL29419900 | 1.00 | RECQL (0.95) | RECQLTDP1MEN1RAD52KMT2A | |
| Oxidopamine SCHEMBL29367988 | 0.97 | RECQL (1.00) | RECQLTDP1MEN1RAD52KMT2A | |
| Oxidopamine SCHEMBL37507 | 0.97 | RECQL (1.00) | RECQLTDP1MEN1RAD52KMT2A | |
| Oxidopamine SCHEMBL718426 | 0.95 | RECQL (1.00) | RECQLTDP1MEN1RAD52KMT2A | |
| Oxidopamine SCHEMBL30862335 | 0.95 | RECQL (1.00) | RECQLTDP1MEN1RAD52KMT2A | |
| Oxidopamine SCHEMBL20398182 | 0.93 | RECQL (0.91) | RECQLTDP1MEN1RAD52KMT2A | |
| SCHEMBL12557128 | 0.83 | RECQL (0.74) | RECQLTDP1MEN1RAD52KMT2A | |
| SCHEMBL1110886 | 0.83 | RECQL (0.74) | RECQLTDP1MEN1RAD52KMT2A | |
| SCHEMBL14452263 | 0.79 | MEN1 (0.68) | RECQLTDP1MEN1RAD52KMT2A | |
| SCHEMBL20409280 | 0.79 | MEN1 (0.68) | RECQLTDP1MEN1RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260143895-A1 | PEROVSKITE SOLAR CELL AND PREPARATION METHOD THEREFOR | TONGWEI SOLAR (CHENGDU) CO., LTD. (CN) | 2026-05-21 | — | — | US | claimed |
| EP-4723846-A1 | PEROVSKITE SOLAR CELL AND PREPARATION METHOD THEREFOR | Tongwei Solar (Chengdu) Co., Ltd. (CN) | 2026-04-08 | — | — | EP | claimed |
| WO-2025011218-A1 | PEROVSKITE SOLAR CELL AND PREPARATION METHOD THEREFOR | 通威太阳能（成都）有限公司 | 2025-01-16 | — | — | WO | claimed |
| CN-117820705-B | Organic silicon heat conduction gasket and preparation method thereof | 深圳市锦联科技有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-117567746-B | Aminosilane coupling agent and application thereof in moisture-heat resistant underfill | 深圳先进电子材料国际创新研究院 | 2024-04-09 | — | — | CN | claimed |
| CN-117567747-B | Surfactant for underfill, and preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2024-04-09 | — | — | CN | claimed |
| CN-117551273-B | Functional auxiliary agent for underfill, preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2024-04-05 | — | — | CN | claimed |
| CN-117820705-A | Organic silicon heat conduction gasket and preparation method thereof | 深圳市锦联科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117586567-A | Rubber hose suitable for ultrahigh pressure cleaning and preparation method thereof | 青岛橡六胶管有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-117567747-A | Surfactant for underfill, and preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2024-02-20 | — | — | CN | claimed |
| CN-115252588-B | Application of 1, 4-hydroquinone and/or 1, 4-hydroquinone derivative in preparing anti-novel coronavirus medicine | 山东达因海洋生物制药股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-116999611-A | Injectable wound dressing with antibacterial and near infrared response functions and preparation method thereof | 清华大学深圳国际研究生院 | 2023-11-07 | — | — | CN | claimed |
| CN-116997193-A | Perovskite solar cell and preparation method thereof | 通威太阳能（成都）有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-114606781-B | Fluorine-free wall cloth fabric coating material and preparation method and application thereof | 湖北工业大学 | 2023-08-15 | — | — | CN | claimed |
| CN-115252588-A | Application of 1, 4-hydroquinone and/or 1, 4-hydroquinone derivative in preparation of anti-novel coronavirus medicines | 山东达因海洋生物制药股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-114606781-A | Fluorine-free wall cloth fabric coating material and preparation method and application thereof | 湖北工业大学 | 2022-06-10 | — | — | CN | claimed |
| US-7846628-B2 | Hole blocking layer containing photoconductors | XEROX CORPORATION (US) | 2010-12-07 | — | — | US | claimed |
| US-7838186-B2 | Photoconductors containing charge transport chelating components | XEROX CORPORATION (US) | 2010-11-23 | — | — | US | claimed |
| US-20080311497-A1 | HOLE BLOCKING LAYER CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2008-12-18 | — | — | US | claimed |
| US-20080286670-A1 | Photoconductors containing charge transport chelating components | XEROX CORPORATION | 2008-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260143895-A1 | PEROVSKITE SOLAR CELL AND PREPARATION METHOD THEREFOR | CDH1, DCX, COMT | ADRA2A 4048/4885SLC6A2 87/4885SLC6A3 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.