Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373416 | 0.88 | MAOA (0.61) | MAOAPOLBMEN1MAPK1KMT2A | |
| SCHEMBL272553 | 0.86 | MAOA (0.64) | MAOACA2KDM4EGLAGAA | |
| SCHEMBL26699113 | 0.84 | MAOA (0.61) | MAOAPOLBMEN1MAPK1KMT2A | |
| SCHEMBL4960212 | 0.83 | MEN1 (0.62) | MAOAPOLBMEN1MAPK1KMT2A | |
| SCHEMBL30741579 | 0.82 | MAOA (0.68) | MAOAPOLBMEN1MAPK1KMT2A | |
| SCHEMBL27777770 | 0.82 | MAOA (0.59) | MAOAPOLBMEN1MAPK1KMT2A | |
| SCHEMBL16016305 | 0.81 | MAOA (0.58) | MAOAPOLBMEN1MAPK1KMT2A | |
| SCHEMBL4927728 | 0.80 | MAOA (0.57) | MAOAPOLBMEN1MAPK1KMT2A | |
| SCHEMBL31398363 | 0.80 | MAOA (0.57) | MAOAPOLBMEN1MAPK1KMT2A | |
| SCHEMBL3974361 | 0.79 | CA12 (0.65) | POLBMEN1KMT2ACA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496653-B1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | OREAL (FR) | 1995-09-13 | — | — | EP | claimed |
| EP-0496653-A1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | L'OREAL (FR) | 1992-07-29 | — | — | EP | claimed |
| US-5034015-A | Fade resistant hair dyes with better coloring ability | L'OREAL (FR) | 1991-07-23 | — | — | US | claimed |
| EP-0360638-A1 | Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor | L'OREAL (FR) | 1990-03-28 | — | — | EP | claimed |
| US-11331336-B2 | Pet food compositions | HILLS PET NUTRITION, INC. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210220385-A1 | PET FOOD COMPOSITIONS | HILL'S PET NUTRITION, INC. (US) | 2021-07-22 | — | — | US | disclosed |
| WO-2020017569-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | 日本ケミファ株式会社 | 2020-01-23 | — | — | WO | disclosed |
| CN-108148005-A | A kind of o-amino phenol derivative and preparation method thereof | 暨南大学 | 2018-06-12 | — | — | CN | disclosed |
| EP-2430019-B1 | COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2013-09-18 | — | — | EP | disclosed |
| US-8399465-B2 | Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene A4 hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2013-03-19 | — | — | US | disclosed |
| US-8362066-B2 | Compounds and methods for treating protein folding disorders | TREVENTIS CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |
| CN-102803210-A | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2012-11-28 | — | — | CN | disclosed |
| CN-1420882-A | Substd. oxoazaheterocyclyl compounds | AVENTIS PHARM PROD INC (US) | 2003-05-28 | — | — | CN | disclosed |
| EP-0598383-B1 | Process for the preparation of 5,6-diacetoxyindole | BRISTOL MYERS SQUIBB CO (US) | 1999-02-03 | — | — | EP | disclosed |
| CN-1036517-C | Process for the preparation of 5,6-diacetoxyindole | BRISTOL MYERS SQUIBB CO (US) | 1997-11-26 | — | — | CN | disclosed |
| CN-1091120-A | 5, the preparation method of 6-diacetylamino indoles | BRISTOL MYERS SQUIBB CO (US) | 1994-08-24 | — | — | CN | disclosed |
| EP-0598383-A1 | Process for the preparation of 5,6-diacetoxyindole | Bristol-Myers Squibb Company (US) | 1994-05-25 | — | — | EP | disclosed |
| US-5262546-A | Process for the preparation of 5,6-diacetoxyindole | CLAIROL, INC. (US) | 1993-11-16 | — | — | US | disclosed |
| US-5034015-A | Fade resistant hair dyes with better coloring ability | L'OREAL (FR) | 1991-07-23 | — | — | US | disclosed |
| EP-0360638-A1 | Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor | L'OREAL (FR) | 1990-03-28 | — | — | EP | disclosed |