SCHEMBL3751049

SCHEMBL3751049

C=CC(=O)c1ccc(O)c(OC)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.66
SLC22A8 Q8TCC7 1/20 0.66
MEN1 O00255 1/20 0.66
RAB9A P51151 1/20 0.66
KMT2A Q03164 1/20 0.66
HTT P42858 1/20 0.64
ABCG2 Q9UNQ0 1/20 0.58
HSD17B2 P37059 1/20 0.55
DPP4 P27487 1/20 0.55
TRPA1 O75762 1/20 0.54
CYP1A2 P05177 1/20 0.54
HSP90AA1 P07900 1/20 0.54
HSP90AB1 P08238 1/20 0.54
BLM P54132 1/20 0.54
KDM4E B2RXH2 1/20 0.53
POLB P06746 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
CXCL12 P48061 2/20 0.51
SNCA P37840 1/20 0.51
TUBB4A P04350 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28643734 0.86 TUBB1 (0.55) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL30307376 0.86 CYP1A2 (0.63) MEN1KMT2AABCG2CYP1A2
SCHEMBL547153 0.86 CYP1A2 (0.63) MEN1KMT2AABCG2CYP1A2
SCHEMBL19655666 0.84 SLC22A6 (0.68) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL20897645 0.83 SLC22A6 (0.62) SLC22A6SLC22A8MEN1RAB9AKMT2A
Vanillic Acid SCHEMBL26622368 0.83 HTT (0.81) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL19632973 0.83 ABCG2 (0.47) SLC22A6SLC22A8MEN1RAB9AKMT2A
Apocynin SCHEMBL31510122 0.82 HTT (0.63) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL4895137 0.81 ALDH1A1 (0.49) SLC22A6SLC22A8MEN1RAB9AKMT2A
Vanillic Acid SCHEMBL30638774 0.81 HTT (0.83) SLC22A6SLC22A8MEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551325-A PVC flame-retardant floor film and preparation method thereof 镇江双晟新材料有限公司 2024-02-13 CN claimed
CN-120005686-A Composition comprising lipase and sulfite 诺维信公司 2025-05-16 CN disclosed
CN-110651038-B Composition comprising lipase and sulfite 诺维信公司 2025-02-18 CN disclosed
CN-118679196-A Polymer stabilizer based on methoxy-hydroxy-benzoic acid, plastic composition, method for stabilizing a plastic composition and stabilizer composition 弗劳恩霍夫应用研究促进协会 2024-09-20 CN disclosed
US-20240207454-A1 NEURO-BEHAVIORAL ASSAY FOR PHYSIOLOGICAL EVALUATION OF WATER-SOLUBLE ANESTHETICS NORTHEASTERN UNIVERSITY 2024-06-27 US disclosed
CN-117551325-A PVC flame-retardant floor film and preparation method thereof 镇江双晟新材料有限公司 2024-02-13 CN disclosed
CN-117304033-A Caffeic acid derivative and preparation method thereof, pharmaceutical composition and application 中国医学科学院药物研究所 2023-12-29 CN disclosed
CN-117069567-A Method for converting oxidized lignin and model compound thereof into high-added-value organic small molecular compound 兰州大学 2023-11-17 CN disclosed
CN-110713866-B Liquid detergent composition for clothing 花王株式会社 2022-05-03 CN disclosed
CN-108342258-B Liquid detergent composition 花王株式会社 2022-04-01 CN disclosed
WO-2013192091-A1 COMPOUNDS WITH (1E, 6E)-1,7-BIS-(3,4-DIMETHOXYPHENYL)-4,4-DISSTITUTED-HEPA-1,6-DIENE-3,5-DIONE STRUCTURAL SCAFFOLD, THEIR BIOLOGICAL ACTIVITY, AND USES THEREOF ANDROSCIENCE CORPORATION (US) 2013-12-27 WO disclosed
US-20130338160-A1 Compounds with (1E, 6E)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof Annji Pharmaceutical Co., Ltd. (TW) 2013-12-19 US disclosed
US-20130261121-A1 Compounds with (1E, 6E)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof Annji Pharmaceutical Co., Ltd. (TW) 2013-10-03 US disclosed
US-8236852-B2 Drugs/cosmetics having at least one (substituted phenyl)-propenal moiety; bioavailability' water solubility; antiandrogens; antiinflammatory and wound healing agents; antiarthritic agents; acne; alopecia, hirsutism; anticarcinogenic agents; cancer of the bladder, liver, breast; Kennedy's disease ANDROSCIENCE CORPORATION (US) 2012-08-07 US disclosed
US-8202905-B2 Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof ANDROSCIENCE CORPORATION (US) 2012-06-19 US disclosed
WO-2011003029-A2 CATALYTIC DISPROPORTIONATION AND CATALYTIC REDUCTION OF CARBON-CARBON AND CARBON-OXYGEN BONDS OF LIGNIN AND OTHER ORGANIC SUBSTRATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-06 WO disclosed
US-20100292342-A1 Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof Annji Pharmaceutical Co., Ltd. (TW) 2010-11-18 US disclosed
EP-2104659-A1 COMPOUNDS WITH (SUBSTITUTED PHENYL)-PROPENAL MOIETY, THEIR DERIVATIVES, BIOLOGICAL ACTIVITY, AND USES THEREOF AndroScience Corporation (US) 2009-09-30 EP disclosed
US-20080188557-A1 Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof Annji Pharmaceutical Co., Ltd. (TW) 2008-08-07 US disclosed
WO-2008085984-A1 COMPOUNDS WITH (SUBSTITUTED PHENYL)-PROPENAL MOIETY, THEIR DERIVATIVES, BIOLOGICAL ACTIVITY, AND USES THEREOF ANDROSCIENCE CORPORATION (US) 2008-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292342-A1 Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof AR, CYP17A1, CYP19A1 SLC22A6 4282/4885SLC22A8 4426/4885MEN1 2395/4885
US-20130338160-A1 Compounds with (1E, 6E)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof AR, BRCA1, CYP17A1 SLC22A6 4512/4885SLC22A8 4714/4885MEN1 2785/4885
US-20080188557-A1 Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof AR, CYP17A1, CYP19A1 SLC22A6 4282/4885SLC22A8 4426/4885MEN1 2395/4885
US-20130261121-A1 Compounds with (1E, 6E)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof AR, BRCA1, CYP17A1 SLC22A6 4512/4885SLC22A8 4714/4885MEN1 2785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.