SCHEMBL3751088

SCHEMBL3751088

CC(=O)O[Si](C)(OC(C)=O)OC(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.30
TSHR P16473 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11895579 0.95 ALDH1A1 (0.30) ALDH1A1TSHRGAA
SCHEMBL63651 0.78 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL2315016 0.77 ALDH1A1 (0.32) ALDH1A1TSHRGAA
SCHEMBL133238 0.77 ALDH1A1 (0.32) ALDH1A1TSHRGAA
SCHEMBL2314856 0.77 ALDH1A1 (0.32) ALDH1A1TSHRGAA
SCHEMBL15662919 0.76
SCHEMBL23781789 0.75 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL18815233 0.73
SCHEMBL13089403 0.73 GAA (0.30) GAA
SCHEMBL10794628 0.73 ALDH1A1 (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2567986-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2022-04-13 EP claimed
US-8716417-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2014-05-06 US claimed
EP-2567986-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2022-04-13 EP disclosed
US-10043658-B2 Precursors for silicon dioxide gap fill ENTEGRIS, INC. (US) 2018-08-07 US disclosed
US-20180130654-A1 PRECURSORS FOR SILICON DIOXIDE GAP FILL TRUIST BANK, AS NOTES COLLATERAL AGENT 2018-05-10 US disclosed
US-20160225615-A1 PRECURSORS FOR SILICON DIOXIDE GAP FILL ENTEGRIS, INC. (US) 2016-08-04 US disclosed
US-8716417-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2014-05-06 US disclosed
US-20120196225-A1 Photo Patternable Coating Compositions of Silicones and Organic-Inorganic Hybrids NAMITEK SPECIALTY MATERIALS CORP. (US) 2012-08-02 US disclosed
US-20100291475-A1 Silicone Coating Compositions LI CHENGHONG 2010-11-18 US disclosed