Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HTR5A | P47898 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375264 | 0.90 | GRIN2B (0.62) | MEN1KMT2ARAB9AHRH3OPRM1 | |
| SCHEMBL1547169 | 0.88 | MEN1 (0.96) | MEN1KMT2ARAB9AHRH3GRIN2B | |
| SCHEMBL16249332 | 0.84 | MEN1 (0.83) | MEN1KMT2ARAB9AHRH3OPRM1 | |
| SCHEMBL24093171 | 0.83 | HRH3 (0.86) | MEN1KMT2ARAB9AHRH3OPRM1 | |
| SCHEMBL8809487 | 0.83 | HRH3 (0.86) | MEN1KMT2ARAB9AHRH3OPRM1 | |
| SCHEMBL29577700 | 0.80 | MEN1 (0.81) | MEN1KMT2ARAB9AHRH3GRIN2B | |
| SCHEMBL17605614 | 0.79 | BCHE (0.54) | MEN1KMT2ARAB9AHRH3OPRM1 | |
| SCHEMBL379455 | 0.79 | HRH3 (0.49) | MEN1KMT2ARAB9AHRH3OPRM1 | |
| SCHEMBL25033800 | 0.79 | HRH3 (0.49) | MEN1KMT2ARAB9AHRH3OPRM1 | |
| SCHEMBL14848246 | 0.79 | ACHE (0.54) | MEN1KMT2ARAB9AHRH3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623898-B2 | Glycine transporter inhibiting substances | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-01-07 | — | — | US | disclosed |
| EP-2409976-A1 | GLYCINE TRANSPORTER INHIBITOR | Taisho Pharmaceutical Co., Ltd. (JP) | 2012-01-25 | — | — | EP | disclosed |
| US-20120010414-A1 | GLYCINE TRANSPORTER INHIBITING SUBSTANCES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010414-A1 | GLYCINE TRANSPORTER INHIBITING SUBSTANCES | SLC18A2, SLC1A2, SLC6A1 | MEN1 2688/4885KMT2A 3137/4885RAB9A 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.