Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 14/20 | 0.63 |
| ▸ | MAOB | P27338 | 12/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3751600 | 1.00 | AOC3 (0.63) | AOC3MAOBCYP2C19RXRARXRB | |
| SCHEMBL3751607 | 1.00 | AOC3 (0.63) | AOC3MAOBCYP2C19RXRARXRB | |
| Hydrochloric Acid SCHEMBL3752160 | 0.99 | AOC3 (0.61) | AOC3MAOBCYP2C19RXRARXRB | |
| Hydrochloric Acid SCHEMBL3752164 | 0.99 | AOC3 (0.61) | AOC3MAOBCYP2C19RXRARXRB | |
| Hydrochloric Acid SCHEMBL3752168 | 0.99 | AOC3 (0.61) | AOC3MAOBCYP2C19RXRARXRB | |
| SCHEMBL2922246 | 0.86 | CYP2C19 (0.65) | AOC3MAOBCYP2C19RXRARXRB | |
| SCHEMBL2915961 | 0.82 | AOC3 (0.61) | AOC3MAOBGAASMN1; SMN2 | |
| SCHEMBL2915970 | 0.82 | AOC3 (0.61) | AOC3MAOBGAASMN1; SMN2 | |
| SCHEMBL2915967 | 0.82 | AOC3 (0.61) | AOC3MAOBGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2923263 | 0.81 | AOC3 (0.59) | AOC3MAOBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222160-B1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD (AU) | 2015-03-18 | — | — | EP | claimed |
| US-8426587-B2 | Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor | PHARMAXIS LTD. (AU) | 2013-04-23 | — | — | US | claimed |
| US-20100298330-A1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD. (AU) | 2010-11-25 | — | — | US | claimed |
| EP-2222160-B1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD (AU) | 2015-03-18 | — | — | EP | disclosed |
| US-8426587-B2 | Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor | PHARMAXIS LTD. (AU) | 2013-04-23 | — | — | US | disclosed |
| US-20100298330-A1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD. (AU) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298330-A1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | VAPA, SLC6A11, VAPB | AOC3 30/4885MAOB 295/4885CYP2C19 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.