Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848524 | 0.91 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL729295 | 0.89 | HPGD (0.49) | HPGDALDH1A1ITGB3ITGA2BDPP4 | |
| SCHEMBL538956 | 0.88 | HPGD (0.57) | HPGDALDH1A1ITGB3ITGA2BDPP4 | |
| SCHEMBL1160326 | 0.88 | HPGD (0.57) | HPGDALDH1A1ITGB3ITGA2BDPP4 | |
| SCHEMBL1160041 | 0.88 | HPGD (0.57) | HPGDALDH1A1ITGB3ITGA2BDPP4 | |
| SCHEMBL1193530 | 0.88 | HPGD (0.57) | HPGDALDH1A1ITGB3ITGA2BDPP4 | |
| SCHEMBL538630 | 0.87 | HPGD (0.48) | HPGDALDH1A1ITGB3ITGA2BDPP4 | |
| SCHEMBL729559 | 0.87 | HPGD (0.56) | HPGDALDH1A1ITGB3ITGA2BF2 | |
| SCHEMBL3684259 | 0.87 | HPGD (0.56) | HPGDALDH1A1ITGB3ITGA2BF2 | |
| SCHEMBL531520 | 0.87 | HPGD (0.56) | HPGDALDH1A1ITGB3ITGA2BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198355-B2 | Nanocomposite compositions of polyamides and sepiolite-type clays | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-12 | — | — | US | claimed |
| US-20100324195-A1 | Nanocomposite compositions of polyamides and Sepiolite-type clays | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-23 | — | — | US | claimed |
| US-20090142585-A1 | Nanocomposite compositions of polyamides, sepiolite-type clays and copper species and articles thereof | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-06-04 | — | — | US | claimed |
| WO-2009061989-A2 | NANOCOMPOSITE COMPOSITIONS OF POLYAMIDES, SEPIOLITE-TYPE CLAYS AND COPPER SPECIES AND ARTICLES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-14 | — | — | WO | claimed |