SCHEMBL729295

SCHEMBL729295

NC(=O)CCCCC(=O)N1CCCCCC1.NC(=O)c1ccc(C(=O)N2CCCCCC2)cc1.NC(=O)c1cccc(C(N)=O)c1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.49
ALDH1A1 P00352 3/20 0.49
USP2 O75604 1/20 0.45
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44
DPP4 P27487 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
F10 P00742 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538630 0.99 HPGD (0.48) HPGDALDH1A1USP2ITGB3ITGA2B
SCHEMBL2406643 0.95 HPGD (0.51) HPGDALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL7946198 0.95 HPGD (0.54) HPGDALDH1A1USP2LMNAPOLB
SCHEMBL9952624 0.94 HPGD (0.53) HPGDALDH1A1USP2SMN1; SMN2LMNA
SCHEMBL1193530 0.92 HPGD (0.57) HPGDALDH1A1ITGB3ITGA2BDPP4
SCHEMBL1160041 0.92 HPGD (0.57) HPGDALDH1A1ITGB3ITGA2BDPP4
SCHEMBL1160326 0.92 HPGD (0.57) HPGDALDH1A1ITGB3ITGA2BDPP4
SCHEMBL538956 0.92 HPGD (0.57) HPGDALDH1A1ITGB3ITGA2BDPP4
SCHEMBL531520 0.91 HPGD (0.56) HPGDALDH1A1ITGB3ITGA2BLMNA
SCHEMBL253101 0.91 HPGD (0.56) HPGDALDH1A1ITGB3ITGA2BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011529988-A 2011-12-15 JP claimed
EP-2307503-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. du Pont de Nemours and Company (US) 2011-04-13 EP claimed
WO-2010014791-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed
WO-2015168075-A1 PHOTOVOLTAIC CELLS WITH IMPROVED BACKSHEET E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-11-05 WO disclosed
EP-2307504-B1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS DU PONT (US) 2015-07-08 EP disclosed
EP-2459639-A1 HEAT RESISTANT POLYAMIDE COMPOSITIONS HAVING HIGH AMINE ENDS E. I. du Pont de Nemours and Company (US) 2012-06-06 EP disclosed
EP-2307504-A1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. du Pont de Nemours and Company (US) 2011-04-13 EP disclosed
WO-2011014556-A1 HEAT RESISTANT POLYAMIDE COMPOSITIONS HAVING HIGH AMINE ENDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-03 WO disclosed
WO-2010014795-A1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO disclosed