SCHEMBL3751632

SCHEMBL3751632

[NH]NS(=O)(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
MMP1 P03956 1/20 0.58
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
MMP8 P22894 1/20 0.58
MMP13 P45452 1/20 0.58
KEAP1 Q14145 3/20 0.56
IL1RN P18510 1/20 0.56
ERAP1 Q9NZ08 1/20 0.56
ALDH1A1 P00352 4/20 0.52
PKM P14618 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
HTR6 P50406 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
BCAT1 P54687 1/20 0.47
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL992761 0.78 CA1 (0.64) CA1CA2MMP1MMP2MMP9
SCHEMBL798074 0.78 CA1 (0.64) CA1CA2MMP1MMP2MMP9
SCHEMBL29653769 0.78 CA1 (0.64) CA1CA2MMP1MMP2MMP9
Potassium SCHEMBL29568431 0.76 CA1 (0.61) CA1CA2MMP1MMP2MMP9
SCHEMBL31120812 0.76 CA1 (0.61) CA1CA2MMP1MMP2MMP9
SCHEMBL5490940 0.76 CA1 (0.61) CA1CA2MMP1MMP2MMP9
SCHEMBL1302465 0.76 CA1 (0.61) CA1CA2MMP1MMP2MMP9
SCHEMBL29011157 0.76 CA1 (0.61) CA1CA2MMP1MMP2MMP9
SCHEMBL6822933 0.76 CA1 (0.61) CA1CA2MMP1MMP2MMP9
SCHEMBL27787022 0.76 CA1 (0.61) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300676-A Herbicidal fluorine-substituted alpha-(5-aryloxynaphthalen-1-yl-oxy)-propionic acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 1994-04-05 US claimed
EP-0553630-A1 Pyridyloxy-naphthalines as herbicides BAYER AG (DE) 1993-08-04 EP claimed
EP-0537538-A1 Derivatives of fluorinated phenoxyphenoxycarboxylic acid as herbicides BAYER AG (DE) 1993-04-21 EP claimed
EP-0534239-A2 Derivatives of alpha-(5-dichlorphenoxy-naphthalen-1-yl-oxy)propionic acid as herbicides BAYER AG (DE) 1993-03-31 EP claimed
EP-0369212-B1 DERIVATIVES OF (HETERO)ARYLOXYNAPHTHALENE, PROCESS, AND (HETERO)ARYLOXYNAPHTHYL AMINES, AND THEIR USE AS HERBICIDES BAYER AG (DE) 1993-02-17 EP claimed
US-5166402-A Herbicidal α-(5-aryloxy-naphthalen-1-yl-oxy)-propionic acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 1992-11-24 US claimed
WO-1992018467-A1 CYANOPHENOXYNAPHTHYL OXYCARBOXYLIC ACID DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1992-10-29 WO claimed
EP-0308755-B1 DERIVATIVES OF 7-(HETERO)ARYLOXY-NAPHTHALEN-2-YLOXY)ALCANOIC ACID BAYER AG (DE) 1992-10-28 EP claimed
EP-0508263-A2 Derivatives of alpha-(5 aryloxy-1 naphthyloxy)-carboxylic acid BAYER AG (DE) 1992-10-14 EP claimed
EP-0315008-B1 DERIVATIVES OF (6-(HETERO)ARYLOXY-NAPHTHALIN-2-YL-OXY)ALCANOIC ACID BAYER AG (DE) 1992-09-09 EP claimed
EP-0309864-B1 ALPHA-(5-ARYLOXY-NAPHTHALEN-1-YL-OXY)-PROPIONIC-ACID DERIVATIVES BAYER AG (DE) 1991-05-22 EP claimed
EP-0384230-A1 Substituted phenoxyphenyl propionic acid derivatives BAYER AG (DE) 1990-08-29 EP claimed
EP-0347679-A1 1,7-Dioxynaphthalene derivatives BAYER AG (DE) 1989-12-27 EP claimed
EP-0338306-A2 Halogen-substituted phenoxybenzyl compounds BAYER AG (DE) 1989-10-25 EP claimed
EP-0315008-A2 Derivatives of (6-(hetero)aryloxy-naphthalin-2-yl-oxy)alcanoic acid BAYER AG (DE) 1989-05-10 EP claimed
EP-0313908-A2 Halogen-substituted phenoxyphenylpropionic acid derivatives BAYER AG (DE) 1989-05-03 EP claimed
EP-0309864-A1 Alpha-(5-aryloxy-naphthalen-1-yl-oxy)-propionic-acid derivatives BAYER AG (DE) 1989-04-05 EP claimed
EP-0272533-A2 Substituted phenoxypyridines BAYER AG (DE) 1988-06-29 EP claimed
EP-0173320-A1 Substituted carbonylphenylsulfonyl guanidines BAYER AG (DE) 1986-03-05 EP claimed
US-4176188-A SUBSTITUTED OXEPANE ORTHO PHARMACEUTICAL CORP. (US) 1979-11-27 US claimed