SCHEMBL3751709

SCHEMBL3751709

CCCCOOOC(=O)C(=O)OOOCCCC

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
ATM Q13315 1/20 0.41
TSHR P16473 5/20 0.39
HPGD P15428 1/20 0.39
HCAR2 Q8TDS4 1/20 0.36
CYP3A4 P08684 1/20 0.36
NAAA Q02083 1/20 0.35
DGKA P23743 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CES2 O00748 2/20 0.35
CES1 P23141 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
ACHE P22303 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3751712 0.89 ALDH1A1 (0.40) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL5808059 0.86 ALDH1A1 (0.44) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL10336102 0.85 ATM (0.57) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL8172195 0.85 ATM (0.57) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL2553635 0.84 ALDH1A1 (0.54) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL3877437 0.84 ALDH1A1 (0.43) ALDH1A1ATMTSHRHPGDHCAR2
Butane SCHEMBL8058020 0.82 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL316751 0.82 ALDH1A1 (0.41) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL4735507 0.80 ALDH1A1 (0.44) ALDH1A1ATMTSHRHPGDNAAA
SCHEMBL28675569 0.80 ALDH1A1 (0.50) ALDH1A1ATMTSHRHPGDHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456257-B2 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION AKZO NOBEL CHEMICALS INT BV (NL) 2020-04-01 EP disclosed
US-7834110-B2 Polymerization in presence of promoters and surfactant; overall polymerization time is reduced by a reduction of the pressure drop time AKZO NOBEL N. V. (NL) 2010-11-16 US disclosed
EP-1456257-B1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION AKZO NOBEL NV (NL) 2009-06-24 EP disclosed
US-20080221266-A1 Polymerization in presence of promoters and surfactant; overall polymerization time is reduced by a reduction of the pressure drop time AKZO NOBEL N.V. (NL) 2008-09-11 US disclosed
US-20050080207-A1 Addition of organic initiators during the pressure drop In vinyl chloride monomer polymerization reactions AKZO NOBEL N.V. (NL) 2005-04-14 US disclosed
EP-1456257-A1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION Akzo Nobel N.V. (NL) 2004-09-15 EP disclosed
WO-2003054039-A1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION REACTIONS AKZO NOBEL N.V. (NL) 2003-07-03 WO disclosed