Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766499 | 0.91 | PNP (0.56) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL3707304 | 0.87 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17521212 | 0.87 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23647921 | 0.87 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL7199411 | 0.87 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL20165850 | 0.85 | PNP (0.64) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL10446997 | 0.85 | PNP (0.64) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL1612645 | 0.85 | PNP (0.56) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL3744956 | 0.85 | PNP (0.60) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL28156309 | 0.85 | PNP (0.62) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838637-B2 | Polyclonal immunoglobulin for use in diagnosis, prevention and treatment of infection, cell proliferative, blood, autoimmune and nervous system disorders | AFFITECH RESEARCH AS (NO) | 2010-11-23 | — | — | US | disclosed |
| US-20090326206-A1 | Single-chain Multiple Antigen-binding Molecule, Its Preparation and Use | AFFITECH RESEARCH AS (NO) | 2009-12-31 | — | — | US | disclosed |
| US-20050004352-A1 | Single-chain multiple antigen-binding molecule, its preparation and use | AFFITECH RESEARCH AS (NO) | 2005-01-06 | — | — | US | disclosed |
| US-20030054409-A1 | Novel complex-forming proteins | JEROME VALERIE (DE) | 2003-03-20 | — | — | US | disclosed |
| EP-0846772-A1 | Multifunctional ligand system for cell-specific transfer of nucleic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-10 | — | — | EP | disclosed |