Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8275350 | 0.96 | CYP3A4 (0.60) | CTSBPPP3CBCYP3A4ABCC1ABCC2 | |
| SCHEMBL5000436 | 0.96 | CYP3A4 (0.60) | CTSBPPP3CBCYP3A4ABCC1ABCC2 | |
| SCHEMBL8351109 | 0.96 | CYP3A4 (0.60) | CTSBPPP3CBCYP3A4ABCC1ABCC2 | |
| SCHEMBL13997826 | 0.96 | CYP3A4 (0.60) | CTSBPPP3CBCYP3A4ABCC1ABCC2 | |
| SCHEMBL845223 | 0.96 | CYP3A4 (0.60) | CTSBPPP3CBCYP3A4ABCC1ABCC2 | |
| SCHEMBL13521381 | 0.94 | CTSB (0.64) | CTSBPPP3CBCYP3A4 | |
| SCHEMBL13123738 | 0.93 | CTSB (0.52) | CTSBPPP3CBCYP3A4ABCC1ABCC2 | |
| SCHEMBL12892241 | 0.93 | CTSB (0.52) | CTSBPPP3CBCYP3A4ABCC1ABCC2 | |
| SCHEMBL14076934 | 0.93 | CTSB (0.52) | CTSBPPP3CBCYP3A4ABCC1ABCC2 | |
| SCHEMBL12892149 | 0.93 | CTSB (0.52) | CTSBPPP3CBCYP3A4ABCC1ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687018-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-01-25 | — | — | EP | disclosed |
| US-7132504-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-11-07 | — | — | US | disclosed |
| US-20050187165-A1 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187165-A1 | Hepatitis C virus inhibitors | HAVCR2, HCCS, RRP1B | CTSB 180/4885PPP3CB 39/4885CYP3A4 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.