⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005195 | 0.89 | KDM4E (0.32) | — | |
| SCHEMBL1998910 | 0.87 | CHRNA7 (0.34) | — | |
| SCHEMBL738216 | 0.82 | — | — | |
| SCHEMBL7906919 | 0.81 | CHRNA7 (0.37) | — | |
| SCHEMBL197609 | 0.77 | — | — | |
| SCHEMBL13290568 | 0.75 | CHRNA7 (0.46) | — | |
| SCHEMBL13290580 | 0.75 | CHRNA7 (0.46) | — | |
| SCHEMBL13290572 | 0.75 | CHRNA7 (0.46) | — | |
| SCHEMBL681912 | 0.75 | CHRNA7 (0.46) | — | |
| SCHEMBL6660188 | 0.75 | CHRNA7 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 798 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611856-B | Piperidine derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-07-05 | — | — | CN | claimed |
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | claimed |
| US-20240174643-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-05-30 | — | — | US | claimed |
| EP-4355741-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2024-04-24 | — | — | EP | claimed |
| EP-4345096-A1 | PIPERIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | Yichang Humanwell Pharmaceutical Co., Ltd. (CN) | 2024-04-03 | — | — | EP | claimed |
| CN-117794923-A | Benzodioxane compound, and preparation method and application thereof | 南京红云生物科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117642389-A | Piperidine derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-03-01 | — | — | CN | claimed |
| CN-117642402-A | Spiropiperidine ring derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-03-01 | — | — | CN | claimed |
| WO-2024024962-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC RING DERIVATIVE | 住友ファーマ株式会社 | 2024-02-01 | — | — | WO | claimed |
| US-20230310428-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-10-05 | — | — | US | claimed |
| WO-2002076986-A1 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO. KG (DE) | 2002-10-03 | — | — | WO | claimed |
| WO-2002066470-A1 | SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2002-08-29 | — | — | WO | claimed |
| WO-2002034760-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-05-02 | — | — | WO | claimed |
| US-6326359-B1 | PURINE DERIVATIVES | PFIZER INC | 2001-12-04 | — | — | US | claimed |
| EP-1140839-A1 | HETEROCYCLIC AMIDES AS INHIBITORS OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2001060835-A1 | PURINE DERIVATIVES | PFIZER LIMITED (GB) | 2001-08-23 | — | — | WO | claimed |
| EP-1121372-A1 | ADENINE DERIVATIVES | Pfizer Limited (GB) | 2001-08-08 | — | — | EP | claimed |
| WO-2000039092-A1 | HETEROCYCLIC AMIDES AS INHIBITORS OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | claimed |
| WO-2000023457-A1 | ADENINE DERIVATIVES | PFIZER LIMITED (GB) | 2000-04-27 | — | — | WO | claimed |
| US-3931198-A | CNS STIMULANTS OR DEPRESSANTS | ABBOTT LABORATORIES (US) | 1976-01-06 | — | — | US | claimed |