⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64047 | 0.78 | — | — | |
| SCHEMBL483206 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL11771179 | 0.78 | — | — | |
| SCHEMBL375314 | 0.77 | — | — | |
| SCHEMBL5746901 | 0.73 | — | — | |
| SCHEMBL77786 | 0.73 | — | — | |
| SCHEMBL21150247 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL989800 | 0.71 | — | — | |
| SCHEMBL6624504 | 0.71 | — | — | |
| SCHEMBL19069125 | 0.71 | CHRNA7 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227967-B2 | Inhibitor compounds of semicarbazide-sensitive amine oxidases | PROXIMAGEN LIMITED (GB) | 2016-01-05 | — | — | US | claimed |
| CN-103180319-A | Inhibitors of semicarabazide - sensitive amine oxidase | PROXIMAGEN LTD | 2013-06-26 | — | — | CN | claimed |
| US-20130102587-A1 | New Enzyme Inhibitor Compounds | PROXIMAGEN LIMITED (GB) | 2013-04-25 | — | — | US | claimed |
| EP-2547677-A2 | INHIBITORS OF SEMICARABAZIDE - SENSITIVE AMINE OXIDASE | Proximagen Limited (GB) | 2013-01-23 | — | — | EP | claimed |
| EP-2240506-B1 | INHIBITORS OF IAP | GENENTECH INC (US) | 2012-12-26 | — | — | EP | claimed |
| US-8247557-B2 | IAP inhibitors | GENENTECH, INC. (US) | 2012-08-21 | — | — | US | claimed |
| US-20120015974-A1 | IMIDAZOPYRIDINE INHIBITORS OF IAP | GENENTECH, INC. (US) | 2012-01-19 | — | — | US | claimed |
| JP-2012500272-A | — | — | 2012-01-05 | — | — | JP | claimed |
| US-8063218-B2 | Imidazopyridine inhibitors of IAP | GENENTECH, INC. (US) | 2011-11-22 | — | — | US | claimed |
| WO-2011113798-A2 | NEW ENZYME INHIBITOR COMPOUNDS | PROXIMAGEN LIMITED (GB) | 2011-09-22 | — | — | WO | claimed |
| EP-2148858-A1 | INHIBITORS OF IAP | Genentech, Inc. (US) | 2010-02-03 | — | — | EP | claimed |
| EP-2125809-A1 | IMIDAZOPYRIDINE INHIBITORS OF IAP | Genentech, Inc. (US) | 2009-12-02 | — | — | EP | claimed |
| US-20090221630-A1 | IAP INHIBITORS | GENENTECH, INC. | 2009-09-03 | — | — | US | claimed |
| WO-2009089502-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2009-07-16 | — | — | WO | claimed |
| WO-2008134679-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2008-11-06 | — | — | WO | claimed |
| EP-1973899-A2 | INHIBITORS OF IAP | Genentech, Inc. (US) | 2008-10-01 | — | — | EP | claimed |
| WO-2008079735-A1 | IMIDAZOPYRIDINE INHIBITORS OF IAP | GENENTECH, INC. (US) | 2008-07-03 | — | — | WO | claimed |
| CN-101142227-A | Novel betulin derivatives, preparation thereof and use thereof | PANACOS PHARMACEUTICALS INC (US) | 2008-03-12 | — | — | CN | claimed |
| WO-2007106192-A2 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2007-09-20 | — | — | WO | claimed |
| US-20060205697-A1 | Novel betulin derivatives, preparation thereof and use thereof | MYREXIS, INC. | 2006-09-14 | — | — | US | claimed |