Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 6/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3752249 | 0.87 | GRM5 (0.46) | GRM5TLR8TLR7NPC1RAB9A | |
| SCHEMBL3666376 | 0.86 | GRM5 (0.45) | GRM5TLR8TLR7NPC1RAB9A | |
| SCHEMBL3667162 | 0.85 | GRM5 (0.48) | GRM5TLR8TLR7NPC1RAB9A | |
| SCHEMBL3672530 | 0.81 | TLR8 (0.55) | GRM5TLR8TLR7NPC1RAB9A | |
| SCHEMBL3664573 | 0.79 | NPC1 (0.60) | GRM5TLR8TLR7NPC1RAB9A | |
| SCHEMBL18711323 | 0.78 | NPC1 (0.59) | GRM5TLR8TLR7NPC1RAB9A | |
| SCHEMBL3750626 | 0.78 | TLR8 (0.41) | GRM5TLR8TLR7NPC1RAB9A | |
| SCHEMBL3750624 | 0.78 | TLR8 (0.41) | GRM5TLR8TLR7NPC1RAB9A | |
| SCHEMBL3746313 | 0.77 | GRM5 (0.49) | GRM5TLR8TLR7NPC1RAB9A | |
| SCHEMBL3672513 | 0.76 | TLR8 (0.53) | GRM5TLR8TLR7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292188-A1 | Compounds Comprising A Cyclobutoxy Group | UCB PHARMA S.A. (BE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292188-A1 | Compounds Comprising A Cyclobutoxy Group | CYP11B2, CYP11B1, CYP4B1 | GRM5 2077/4885TLR8 4686/4885TLR7 3431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.