Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485862 | 0.91 | GSK3B (0.60) | GSK3BCYP2D6 | |
| SCHEMBL2486490 | 0.91 | GSK3B (0.47) | GSK3BCYP2D6 | |
| SCHEMBL2491255 | 0.89 | GSK3B (0.51) | GSK3BCYP2D6 | |
| SCHEMBL2487402 | 0.89 | GSK3B (0.51) | GSK3BCYP2D6 | |
| SCHEMBL3749271 | 0.88 | GSK3B (0.43) | GSK3BCYP2D6 | |
| SCHEMBL2491257 | 0.79 | GSK3B (0.47) | GSK3BCYP2D6 | |
| SCHEMBL3744211 | 0.79 | GSK3B (0.52) | GSK3BCYP2D6 | |
| SCHEMBL2491912 | 0.76 | GSK3B (0.40) | GSK3B | |
| SCHEMBL2527052 | 0.74 | MAP4K4 (0.41) | GSK3BCYP2D6 | |
| SCHEMBL3737510 | 0.74 | GSK3B (0.46) | GSK3BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292205-A1 | Pyrimidone Compounds As GSK-3 Inhibitors | PFIZER INC. (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292205-A1 | Pyrimidone Compounds As GSK-3 Inhibitors | GSK3B, GSK3A, GSKIP | GSK3B 1/4885CYP2D6 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.