SCHEMBL375459

SCHEMBL375459

C=C(C)C(=O)N(C)CCCCC

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 7/20 0.44
TSHR P16473 2/20 0.41
DNM1 Q05193 3/20 0.39
SIGMAR1 Q99720 1/20 0.36
S1PR2 O95136 1/20 0.36
S1PR1 P21453 1/20 0.36
S1PR3 Q99500 1/20 0.36
S1PR5 Q9H228 1/20 0.36
ALDH1A1 P00352 1/20 0.35
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
KDM5A P29375 1/20 0.35
KDM5C P41229 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
KDM5B Q9UGL1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931110 0.98 EPHX2 (0.46) EPHX2TSHRDNM1S1PR2S1PR1
SCHEMBL1578700 0.98 EPHX2 (0.46) EPHX2TSHRDNM1S1PR2S1PR1
SCHEMBL1578436 0.98 EPHX2 (0.46) EPHX2TSHRDNM1S1PR2S1PR1
SCHEMBL1578737 0.98 EPHX2 (0.46) EPHX2TSHRDNM1S1PR2S1PR1
SCHEMBL1930922 0.98 EPHX2 (0.46) EPHX2TSHRDNM1S1PR2S1PR1
SCHEMBL375653 0.98 EPHX2 (0.46) EPHX2TSHRDNM1S1PR2S1PR1
SCHEMBL1578939 0.98 EPHX2 (0.46) EPHX2TSHRDNM1S1PR2S1PR1
SCHEMBL1578997 0.98 EPHX2 (0.46) EPHX2TSHRDNM1S1PR2S1PR1
SCHEMBL1579083 0.98 EPHX2 (0.46) EPHX2TSHRDNM1S1PR2S1PR1
SCHEMBL1578404 0.98 EPHX2 (0.46) EPHX2TSHRDNM1S1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2408886-B1 FAST DRYING AMPHOLYTIC POLYMERS FOR CLEANING COMPOSITIONS BASF SE (DE) 2013-11-13 EP claimed
US-8232236-B2 Fast drying ampholytic polymers for cleaning compositions BASF SE (DE) 2012-07-31 US claimed
EP-2408886-A2 FAST DRYING AMPHOLYTIC POLYMERS FOR CLEANING COMPOSITIONS BASF SE (DE) 2012-01-25 EP claimed
US-20100240563-A1 Fast drying ampholytic polymers for cleaning compositions BASF SE (DE) 2010-09-23 US claimed
WO-2010107554-A2 FAST DRYING AMPHOLYTIC POLYMERS FOR CLEANING COMPOSITIONS CIBA CORPORATION (US) 2010-09-23 WO claimed
EP-2687533-B1 Acrylamide derivatives as FAB I inhibitors DEBIOPHARM INT SA (CH) 2017-07-19 EP disclosed
EP-2054422-B1 ACRYLAMIDE DERIVATIVES AS FAB I INHIBITORS DEBIOPHARM INT SA (CH) 2017-06-14 EP disclosed
US-8895545-B2 Acrylamide derivatives as Fab I inhibitors DEBIOPHARM INTERNATIONAL SA (CH) 2014-11-25 US disclosed
WO-2014079756-A1 ANTIADHESIVE POLYMERS FOR MICROBE-REPULSIVE TEXTILE FINISHING HENKEL AG & CO. KGAA (DE) 2014-05-30 WO disclosed
EP-2687533-A2 Acrylamide derivatives as FAB I inhibitors Affinium Pharmaceuticals, Inc. (CA) 2014-01-22 EP disclosed
EP-2408886-B1 FAST DRYING AMPHOLYTIC POLYMERS FOR CLEANING COMPOSITIONS BASF SE (DE) 2013-11-13 EP disclosed
US-20130237523-A1 ACRYLAMIDE DERIVATIVES AS FAB I INHIBITORS AFFINIUM PHARMACEUTICALS, INC. (CA) 2013-09-12 US disclosed
US-8524116-B2 Multilayer sheet containing optically anisotropic layer containing liquid crystal compound and cellulose ester with polymer FUJIFILM CORPORATION (JP) 2013-09-03 US disclosed
US-8318720-B2 Acrylamide derivatives as Fab I inhibitors AFFINIUM PHARMACEUTICALS, INC. (CA) 2012-11-27 US disclosed
US-8232236-B2 Fast drying ampholytic polymers for cleaning compositions BASF SE (DE) 2012-07-31 US disclosed
WO-2012010700-A1 PREVENTION OF BACTERIAL ADHESION HENKEL AG & CO. KGAA (DE) 2012-01-26 WO disclosed
EP-2408886-A2 FAST DRYING AMPHOLYTIC POLYMERS FOR CLEANING COMPOSITIONS BASF SE (DE) 2012-01-25 EP disclosed
US-20100240563-A1 Fast drying ampholytic polymers for cleaning compositions BASF SE (DE) 2010-09-23 US disclosed
WO-2010107554-A2 FAST DRYING AMPHOLYTIC POLYMERS FOR CLEANING COMPOSITIONS CIBA CORPORATION (US) 2010-09-23 WO disclosed
US-20100130470-A1 ACRYLAMIDE DERIVATIVES AS FAB I INHIBITORS AFFINIUM PHARMACEUTICALS, INC. 2010-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130237523-A1 ACRYLAMIDE DERIVATIVES AS FAB I INHIBITORS ACR, DBI, AADAC EPHX2 4549/4885TSHR 3272/4885DNM1 1974/4885
US-20100130470-A1 ACRYLAMIDE DERIVATIVES AS FAB I INHIBITORS ACR, DBI, AADAC EPHX2 4549/4885TSHR 3272/4885DNM1 1974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.