Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 2/20 | 0.32 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232621 | 0.97 | LMNA (0.53) | LMNAALDH1A1THRBTYMPKDM4E | |
| Hydrochloric Acid SCHEMBL7626501 | 0.93 | LMNA (0.50) | LMNAALDH1A1THRBTYMPKDM4E | |
| SCHEMBL1898456 | 0.88 | LMNA (0.44) | LMNAALDH1A1THRBTYMPKDM4E | |
| Hydrochloric Acid SCHEMBL28419851 | 0.85 | LMNA (0.42) | LMNAALDH1A1THRBTYMPKDM4E | |
| SCHEMBL24159905 | 0.84 | — | — | |
| SCHEMBL4935953 | 0.83 | LMNA (0.40) | LMNAALDH1A1THRBTYMPKDM4E | |
| SCHEMBL6484167 | 0.83 | LMNA (0.40) | LMNAALDH1A1THRBTYMPKDM4E | |
| SCHEMBL15540151 | 0.83 | TDP1 (0.45) | LMNAALDH1A1THRBTYMPKDM4E | |
| SCHEMBL5908059 | 0.83 | LMNA (0.40) | LMNAALDH1A1THRBTYMPKDM4E | |
| SCHEMBL14663224 | 0.81 | LMNA (0.44) | LMNAALDH1A1THRBTYMPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100303734-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-12-02 | — | — | US | disclosed |
| US-20100303734-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-12-02 | — | — | US | disclosed |
| US-20100303734-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-12-02 | — | — | US | disclosed |
| EP-2231200-A1 | CONTRAST AGENTS | GE Healthcare AS (NO) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009071605-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009071605-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303734-A1 | CONTRAST AGENTS | C1R, CNKSR1, C5 | LMNA 2025/4885ALDH1A1 2186/4885THRB 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.