Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27773316 | 0.97 | EPHX1 (0.52) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL9821330 | 0.75 | EPHX1 (0.60) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL3885036 | 0.74 | EPHX1 (0.40) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL7323638 | 0.74 | EPHX1 (0.46) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL11703750 | 0.72 | SHBG (0.44) | EPHX1SHBGTP53LMNAMAPT | |
| SCHEMBL14951097 | 0.72 | TP53 (0.58) | EPHX1SHBGTP53LMNAALDH1A1 | |
| SCHEMBL6518166 | 0.71 | EPHX1 (0.55) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL3887311 | 0.71 | EPHX1 (0.55) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL11003896 | 0.71 | SHBG (0.62) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL1323089 | 0.71 | EPHX1 (0.55) | EPHX1SHBGTP53LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817362-B1 | Crosslinkable poly(oxyalkylene)-containing polyamide prepolymers | NOVARTIS AG (CH) | 2010-09-22 | — | — | EP | claimed |
| US-20070244211-A1 | Crosslinkable poly(oxyalkylene)-containing polyamide prepolymers | NOVARTIS AG (CH) | 2007-10-18 | — | — | US | claimed |
| EP-1817362-A1 | CROSSLINKABLE POLY(OXYALKYLENE)-CONTAINING POLYAMIDE PREPOLYMERS | Novartis AG (CH) | 2007-08-15 | — | — | EP | claimed |
| WO-2006053777-A1 | CROSSLINKABLE POLY(OXYALKYLENE)-CONTAINING POLYAMIDE PREPOLYMERS | NOVARTIS AG (CH) | 2006-05-26 | — | — | WO | claimed |