⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15145099 | 0.82 | — | — | |
| SCHEMBL2384197 | 0.82 | — | — | |
| SCHEMBL9815367 | 0.63 | TSHR (0.30) | — | |
| SCHEMBL10256463 | 0.59 | — | — | |
| SCHEMBL10257118 | 0.59 | ALDH1A1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL11909936 | 0.57 | — | — | |
| SCHEMBL5901216 | 0.57 | TSHR (0.31) | — | |
| SCHEMBL19886137 | 0.55 | — | — | |
| SCHEMBL9547219 | 0.54 | MCL1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL10382215 | 0.54 | APEX1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354102-B2 | Antibodies directed to mGluR7 | HOFFMANN-LA ROCHE INC. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20100303802-A1 | ANTIBODY DIRECTED TO G PROTEIN COUPLED RECEPTORS (GPCR) | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-02 | — | — | US | disclosed |
| EP-1222309-A4 | HUMAN RNASE H AND OLIGONUCLEOTIDE COMPOSITIONS THEREOF | ISIS PHARMACEUTICALS INC (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-1222309-A1 | HUMAN RNASE H AND OLIGONUCLEOTIDE COMPOSITIONS THEREOF | ISIS PHARMACEUTICALS, INC. (US) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001023613-A1 | HUMAN RNASE H AND OLIGONUCLEOTIDE COMPOSITIONS THEREOF | ISIS PHARMACEUTICALS, INC. (US) | 2001-04-05 | — | — | WO | disclosed |