SCHEMBL3755203

SCHEMBL3755203

CC(C)O[Si](C)(C)CC1CO1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26658369 0.80 ALDH1A1 (0.31) ALDH1A1
SCHEMBL12851683 0.75 ALDH1A1 (0.37) ALDH1A1TSHRMAPK1
SCHEMBL3068447 0.73
SCHEMBL3795919 0.71
SCHEMBL13038579 0.71 ALDH1A1 (0.34) ALDH1A1TSHRMAPK1
SCHEMBL3742108 0.70 TSHR (0.55) ALDH1A1TSHRMAPK1
SCHEMBL3058883 0.70 SMN1; SMN2 (0.34) ALDH1A1TSHRMAPK1
SCHEMBL7109108 0.69 ALDH1A1 (0.33) ALDH1A1
Oxirane SCHEMBL5964644 0.67 CHRM2 (0.31) ALDH1A1
SCHEMBL705523 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7834120-B2 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-11-16 US disclosed
EP-1645560-B1 Monofunctional monomer having cage oligosiloxane structure and method of making SHINETSU CHEMICAL CO (JP) 2008-05-28 EP disclosed
EP-1645560-A1 Monofunctional monomer having cage oligosiloxane structure and method of making Shin-Etsu Chemical Co., Ltd. (JP) 2006-04-12 EP disclosed
US-20060074213-A1 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-04-06 US disclosed