SCHEMBL3755405

SCHEMBL3755405

CCON=C(C(=O)O)c1ccccc1COc1ccc(C=C(F)Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.43
MAPT P10636 3/20 0.42
KMT2A Q03164 3/20 0.42
HPGD P15428 1/20 0.42
HIF1A Q16665 8/20 0.39
KDM4E B2RXH2 2/20 0.38
NR4A2 P43354 1/20 0.38
PTPN1 P18031 2/20 0.38
PTPRC P08575 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
HTT P42858 2/20 0.36
MEN1 O00255 2/20 0.36
RAD52 P43351 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ITGB1 P05556 1/20 0.36
ITGA4 P13612 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3758380 0.92 NR1H4 (0.45) NR1H4MAPTKMT2AHPGDHIF1A
SCHEMBL3755609 0.92 NR1H4 (0.45) NR1H4MAPTKMT2AHPGDHIF1A
SCHEMBL3751696 0.90 NR1H4 (0.43) NR1H4MAPTKMT2AHPGDHIF1A
SCHEMBL3759713 0.89 HIF1A (0.49) KMT2AHIF1AKDM4ENR4A2MEN1
SCHEMBL3752980 0.88 NR1H4 (0.45) NR1H4MAPTKMT2AHPGDHIF1A
SCHEMBL8618332 0.84 HIF1A (0.50) HIF1AKDM4ENR4A2PTPN1PTPRC
SCHEMBL8618330 0.84 HIF1A (0.50) HIF1AKDM4ENR4A2PTPN1PTPRC
SCHEMBL3751654 0.82 HIF1A (0.52) KMT2AHIF1AKDM4ENR4A2MAOA
SCHEMBL3755404 0.80 HIF1A (0.61) NR1H4MAPTKMT2AHPGDHIF1A
SCHEMBL8618307 0.80 HIF1A (0.48) HIF1AKDM4ENR4A2PTPN1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 NR1H4 3791/4885MAPT 1657/4885KMT2A 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.