SCHEMBL3755609

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3751696	0.92	NR1H4 (0.43)	NR1H4MAPTKMT2AHPGDHIF1A
	SCHEMBL3755405	0.92	NR1H4 (0.43)	NR1H4MAPTKMT2AHPGDHIF1A
	SCHEMBL3751654	0.90	HIF1A (0.52)	KMT2AHIF1ANR4A2KDM4EMAOA
	SCHEMBL3758380	0.89	NR1H4 (0.45)	NR1H4MAPTKMT2AHPGDHIF1A
	SCHEMBL3752980	0.89	NR1H4 (0.45)	NR1H4MAPTKMT2AHPGDHIF1A
	SCHEMBL8618332	0.86	HIF1A (0.50)	HIF1ANR4A2KDM4EPTPN1PTPRC
	SCHEMBL8618330	0.86	HIF1A (0.50)	HIF1ANR4A2KDM4EPTPN1PTPRC
	SCHEMBL3688079	0.86	MRGPRX4 (0.48)	MAPTKMT2AHPGDHIF1AHTT
	SCHEMBL3687655	0.86	HIF1A (0.43)	NR1H4MAPTKMT2AHIF1ANR4A2
	SCHEMBL3694297	0.85	HIF1A (0.42)	MAPTKMT2AHIF1AHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.