SCHEMBL3756074

SCHEMBL3756074

CCC(CC)CCC(=O)OCC(CC)CC

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
CYP3A4 P08684 2/20 0.61
ATM Q13315 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
LMNA P02545 2/20 0.43
ALDH1A1 P00352 2/20 0.43
RECQL P46063 1/20 0.42
MAPT P10636 1/20 0.40
CA2 P00918 3/20 0.38
KDM4E B2RXH2 1/20 0.38
DUSP3 P51452 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PRKCA P17252 1/20 0.36
PRKCE Q02156 1/20 0.36
PRKCQ Q04759 1/20 0.36
PRKCD Q05655 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3740920 0.89 TSHR (0.62) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL31461597 0.88 TSHR (0.58) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL420275 0.84 CYP3A4 (0.75) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL6912700 0.84 TSHR (0.63) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL7291814 0.84 L3MBTL1 (0.52) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL3740929 0.84 TSHR (0.69) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL4146581 0.83 CYP3A4 (0.83) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL418613 0.83 CYP3A4 (0.72) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL3742944 0.83 CYP3A4 (0.72) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL3750378 0.83 CYP3A4 (0.72) TSHRCYP3A4ATMTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079850-B2 Cosmetic compositions containing esters of 2-ethylbutanol COGNIS IP MANAGEMENT GMBH (DE) 2015-07-14 US disclosed
CN-101505833-B Cosmetic compositions containing ester obtained from 2-butyl-1-octanol COGNIS IP MAN GMBH 2014-05-21 CN disclosed
US-20100298432-A1 Cosmetic Compositions Containing Esters of 2-Butyloctanol COGNIS IP MANAGEMENT GMBH (DE) 2010-11-25 US disclosed
US-20100292328-A1 Cosmetic Compositions Containing Esters of 2-ethylbutanol COGNIS IP MANAGEMENT GMBH (DE) 2010-11-18 US disclosed
CN-101505832-A Cosmetic compositions containing an ester obtained from 2-ethylbutanol COGNIS IP MAN GMBH (DE) 2009-08-12 CN disclosed
CN-101505833-A Cosmetic compositions containing ester obtained from 2-butyl-1-octanol COGNIS IP MAN GMBH (DE) 2009-08-12 CN disclosed