Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3756545 | 0.86 | EPHX2 (0.43) | EPHX2ALOX5LOXL2NPC1RAB9A | |
| SCHEMBL3756541 | 0.86 | EPHX2 (0.43) | EPHX2ALOX5LOXL2NPC1RAB9A | |
| SCHEMBL3746479 | 0.85 | LOXL2 (0.43) | EPHX2ALOX5LOXL2NPC1RAB9A | |
| SCHEMBL15713544 | 0.83 | EPHX2 (0.45) | EPHX2ALOX5LOXL2HDAC6MAPT | |
| SCHEMBL21104409 | 0.82 | EPHX2 (0.46) | EPHX2ALOX5LOXL2HDAC6MAPT | |
| SCHEMBL15713307 | 0.82 | EPHX2 (0.47) | EPHX2ALOX5LOXL2HDAC6MAPT | |
| SCHEMBL15689586 | 0.82 | HDAC6 (0.51) | EPHX2ALOX5LOXL2NPC1HDAC6 | |
| SCHEMBL15689757 | 0.82 | HDAC6 (0.48) | EPHX2ALOX5LOXL2NPC1RAB9A | |
| SCHEMBL15689693 | 0.82 | HDAC6 (0.47) | EPHX2ALOX5LOXL2NPC1HDAC6 | |
| SCHEMBL3746477 | 0.81 | LOXL2 (0.45) | EPHX2ALOX5LOXL2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203219-B1 | SUBSTITUTED BENZAMIDINES AS ANTIBACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2015-02-25 | — | — | EP | disclosed |
| US-8415383-B2 | Substituted benzamidines as antibacterial agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-04-09 | — | — | US | disclosed |
| US-20100298388-A1 | SUBSTITUTED BENAMIDINES AS ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD. (GB) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298388-A1 | SUBSTITUTED BENAMIDINES AS ANTIBACTERIAL AGENTS | ALK, CBR3, CBR1 | EPHX2 2510/4885ALOX5 1534/4885LOXL2 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.