SCHEMBL3756748

SCHEMBL3756748

CCCCCCCCCCCCCCCCOC[C@H](CO)OCCCCCCCCCCCCCCCC

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.63
LPAR1 Q92633 7/20 0.60
LPAR3 Q9UBY5 7/20 0.60
LPAR2 Q9HBW0 4/20 0.60
ALDH1A1 P00352 1/20 0.54
CNR1 P21554 1/20 0.54
CNR2 P34972 1/20 0.54
DNM1 Q05193 1/20 0.52
HTT P42858 2/20 0.52
TLR2 O60603 2/20 0.51
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPT P10636 1/20 0.50
LPAR6 P43657 3/20 0.49
LPAR4 Q99677 3/20 0.49
LPAR5 Q9H1C0 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7060157 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL5249703 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL7063456 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL10561321 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL103054 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL2417250 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL25266425 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL15016340 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL7058701 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL7063486 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071559-A Methods and compositions for treating Rett syndrome 亲神经剂生物科学有限公司 2018-12-21 CN claimed
CN-104382853-A Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics MARINA BIOTECH INC 2015-03-04 CN claimed
US-12473314-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2025-11-18 US disclosed
EP-4635481-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2025-10-22 EP disclosed
EP-4218722-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2025-08-20 EP disclosed
EP-4537828-A2 PHOSPHOLIPID COMPOUNDS AND USES THEREOF Gilead Sciences, Inc. (US) 2025-04-16 EP disclosed
EP-4200301-B1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES INC (US) 2025-02-26 EP disclosed
WO-2024251108-A1 IONIZABLE LIPID COMPOUND, LIPID CARRIER COMPRISING SAME AND USE THEREOF 北京因诺惟康医药科技有限公司 2024-12-12 WO disclosed
CN-118955699-A Broadly neutralizing anti-HIV antibodies 洛克菲勒大学 2024-11-15 CN disclosed
WO-2024212958-A1 IONIZABLE LIPID COMPOUND, LIPID CARRIER COMPRISING SAME, AND APPLICATION 北京因诺惟康医药科技有限公司 2024-10-17 WO disclosed
WO-2024192906-A1 LIPID COMPOUND FOR DELIVERING THERAPEUTIC AGENT, PREPARATION METHOD THEREFOR, AND USE THEREOF 尧唐(上海)生物科技有限公司 2024-09-26 WO disclosed
US-20140294782-A1 Reprogramming of Cellular Adhesion US ARMY, SECRETARY OF THE ARMY 2014-10-02 US disclosed
EP-2773327-A1 REPROGRAMMING OF CELLULAR ADHESION The Regents of The University of California (US) 2014-09-10 EP disclosed
US-8808703-B2 Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) 2014-08-19 US disclosed
WO-2013067203-A1 REPROGRAMMING OF CELLULAR ADHESION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-05-10 WO disclosed
US-20130065861-A1 COMPOUNDS (CYSTEIN BASED LIPOPEPTIDES) AND COMPOSITIONS AS TLR2 AGONISTS USED FOR TREATING INFECTIONS, INFLAMMATIONS, RESPIRATORY DISEASES ETC. IRM LLC (BM) 2013-03-14 US disclosed
US-20110064794-A1 Drug Delivery System, its Preparation Process and Use SHENYANG PHARMACEUTICAL UNIVERSITY (CN) 2011-03-17 US disclosed
US-20100297156-A1 ANALOGUES OF PHOSPHATIDYLINOSITOL MANNOSIDES INDUSTRIAL RESEARCH LIMITED (NZ) 2010-11-25 US disclosed
US-20100297156-A1 ANALOGUES OF PHOSPHATIDYLINOSITOL MANNOSIDES INDUSTRIAL RESEARCH LIMITED (NZ) 2010-11-25 US disclosed
US-4847376-A COLORIMETRIC ANALYSIS BOEHRINGER MANNHEIM GMBH (DE) 1989-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065861-A1 COMPOUNDS (CYSTEIN BASED LIPOPEPTIDES) AND COMPOSITIONS AS TLR2 AGONISTS USED FOR TREATING INFECTIONS, INFLAMMATIONS, RESPIRATORY DISEASES ETC. TLR2, TLR4, TLR3 USP2 1960/4885LPAR1 81/4885LPAR3 68/4885
US-20100297156-A1 ANALOGUES OF PHOSPHATIDYLINOSITOL MANNOSIDES PIK3CA, PIK3CB, PIK3CG USP2 4005/4885LPAR1 515/4885LPAR3 401/4885
US-12473314-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 USP2 4298/4885LPAR1 87/4885LPAR3 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.