Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.47 |
| ▸ | KDR | P35968 | 12/20 | 0.47 |
| ▸ | MST1R | Q04912 | 11/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534756 | 0.91 | MST1R (0.47) | METKDRMST1R | |
| SCHEMBL3568097 | 0.90 | MET (0.51) | METKDRMST1R | |
| SCHEMBL2670833 | 0.89 | MET (0.46) | METKDRMST1R | |
| SCHEMBL2670836 | 0.89 | MET (0.46) | METKDRMST1R | |
| SCHEMBL10164514 | 0.84 | MET (0.44) | METKDRMST1R | |
| SCHEMBL16187724 | 0.83 | MET (0.52) | METKDRMST1R | |
| SCHEMBL2530838 | 0.83 | MET (0.48) | METKDRMST1R | |
| SCHEMBL13166965 | 0.83 | MET (0.46) | METKDRMST1R | |
| SCHEMBL2670642 | 0.82 | MET (0.45) | METKDRMST1R | |
| SCHEMBL1674666 | 0.82 | MST1R (0.43) | METKDRMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2183254-B1 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | METHYLGENE INC (CA) | 2017-06-21 | — | — | EP | disclosed |
| EP-2183254-A1 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | MethylGene Inc. (CA) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009026717-A1 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |