SCHEMBL3757327

SCHEMBL3757327

OP(O)c1ccccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 2/20 0.48
HPGD P15428 1/20 0.48
BCL2L1 Q07817 1/20 0.48
BACE1 P56817 1/20 0.44
CYP2A6 P11509 1/20 0.42
MAPK1 P28482 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
BCAT2 O15382 2/20 0.40
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
ALOX5 P09917 1/20 0.38
DPP4 P27487 1/20 0.38
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30753793 1.00 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL2474597 0.84 MEN1 (0.33) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL31066741 0.82 ALDH1A1 (0.41) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL15260401 0.82 ALDH1A1 (0.41) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL2679731 0.82 ALDH1A1 (0.41) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL6292080 0.79 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL12004263 0.78 ALDH1A1 (0.57) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL30662000 0.78 ALDH1A1 (0.57) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL5081022 0.75 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL10792406 0.75 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDBCL2L1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104981473-B Azine metal phosphates as flame-retardant materials J.M.休伯有限公司 2021-06-29 CN disclosed
EP-1858946-B1 COMPOSITIONS OF ETHYLENE/ALPHA-OLEFIN MULTI-BLOCK INTERPOLYMER FOR BLOWN FILMS WITH HIGH HOT TACK DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-25 EP disclosed
US-9352537-B2 Compositions of ethylene/α-olefin multi-block interpolymer suitable for films DOW GLOBAL TECHNOLOGIES LLC (US) 2016-05-31 US disclosed
US-9102128-B2 Multilayer films DOW GLOBAL TECHNOLOGIES LLC (US) 2015-08-11 US disclosed
EP-2799235-A1 Multilayer films Dow Global Technologies LLC (US) 2014-11-05 EP disclosed
US-8816006-B2 Compositions of ethylene/α-olefin multi-block interpolymer suitable for films DOW GLOBAL TECHNOLOGIES LLC (US) 2014-08-26 US disclosed
US-20140141228-A1 Compositions of Ethylene/Alpha-Olefin Multi-Block Interpolymer Suitable for Films DOW GLOBAL TECHNOLOGIES LLC (US) 2014-05-22 US disclosed
US-7842770-B2 Compositions of ethylene/α-olefin multi-block interpolymer for blown films with high hot tack DOW GLOBAL TECHNOLOGIES INC. (US) 2010-11-30 US disclosed
US-20090324914-A1 COMPOSITIONS OF ETHYLENE / ALPHA-OLEFIN MULTI-BLOCK INTERPOLYMER FOR BLOWN FILMS WITH HIGH HOT TACK DOW GLOBAL TECHNOLOGIES INC. (US) 2009-12-31 US disclosed
EP-1871815-B1 COMPOSITIONS OF ETHYLENE/ALPHA-OLEFIN MULTI-BLOCK INTERPOLYMER SUITABLE FOR FILMS DOW GLOBAL TECHNOLOGIES INC (US) 2009-11-25 EP disclosed
US-5525695-A OLEFIN POLYMERS PRODUCED IN A CONTINUOUS POLYMERIZATION PROCESS IN PRESENCE OF COORDINATION CATALYST HAVING CONSTRAINED GEOMETRY THE DOW CHEMICAL COMPANY (US) 1996-06-11 US disclosed
WO-1996012762-A1 POLYOLEFIN COMPOSITIONS EXHIBITING HEAT RESISTIVITY, LOW HEXANE-EXTRACTIVES AND CONTROLLED MODULUS THE DOW CHEMICAL COMPANY (US) 1996-05-02 WO disclosed
WO-1996007680-A1 PLASTIC LINEAR LOW DENSITY POLYETHYLENE THE DOW CHEMICAL COMPANY (US) 1996-03-14 WO disclosed
WO-1996003441-A1 CHLORINATED AND CHLOROSULFONATED ELASTIC SUBSTANTIALLY LINEAR OLEFIN POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-02-08 WO disclosed
EP-0665863-A1 FILM FOR PACKAGING PURPOSES THE DOW CHEMICAL COMPANY (US) 1995-08-09 EP disclosed
US-5380810-A Narrow molecular weight distribution THE DOW CHEMICAL COMPANY (US) 1995-01-10 US disclosed
EP-0608369-A1 ELASTIC SUBSTANTIALLY LINEAR OLEFIN POLYMERS. DOW CHEMICAL CO (US) 1994-08-03 EP disclosed
WO-1994009060-A1 FILM FOR PACKAGING PURPOSES THE DOW CHEMICAL COMPANY (US) 1994-04-28 WO disclosed
US-5272236-A Elastic substantially linear olefin polymers THE DOW CHEMICAL COMPANY (US) 1993-12-21 US disclosed
WO-1993008221-A2 ELASTIC SUBSTANTIALLY LINEAR OLEFIN POLYMERS THE DOW CHEMICAL COMPANY (US) 1993-04-29 WO disclosed