Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681542 | 1.00 | NR5A1 (0.38) | NR5A1TSHRPLA2G2ATP53ALDH1A1 | |
| SCHEMBL1543863 | 1.00 | NR5A1 (0.38) | NR5A1TSHRPLA2G2ATP53ALDH1A1 | |
| SCHEMBL4624291 | 0.92 | LTA4H (0.33) | NR5A1TSHRLTA4HTHRATHRB | |
| SCHEMBL5453657 | 0.86 | — | — | |
| SCHEMBL4622609 | 0.82 | NR5A1 (0.44) | NR5A1TSHRPLA2G2ATP53ALDH1A1 | |
| SCHEMBL4623426 | 0.82 | NR5A1 (0.44) | NR5A1TSHRPLA2G2ATP53ALDH1A1 | |
| SCHEMBL1871053 | 0.82 | NR5A1 (0.44) | NR5A1TSHRPLA2G2ATP53ALDH1A1 | |
| SCHEMBL15211843 | 0.82 | NR5A1 (0.44) | NR5A1TSHRPLA2G2ATP53ALDH1A1 | |
| SCHEMBL4622605 | 0.82 | NR5A1 (0.44) | NR5A1TSHRPLA2G2ATP53ALDH1A1 | |
| SCHEMBL4623189 | 0.82 | NR5A1 (0.44) | NR5A1TSHRPLA2G2ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100310647-A1 | Enzymatic Synthesis of Polymers | UNIVERSITY OF MASSACHUSETTS (US) | 2010-12-09 | — | — | US | claimed |
| US-20060094857-A1 | Enzymatic synthesis of polymers | ARMY, UNITED STATES AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2006-05-04 | — | — | US | claimed |
| EP-0704094-B1 | POLYMERS FOR OPTICAL DEVICES | CAMBRIDGE DISPLAY TECH LTD (GB) | 2001-08-08 | — | — | EP | claimed |
| WO-1994029883-A1 | POLYMERS FOR OPTICAL DEVICES | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 1994-12-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310647-A1 | Enzymatic Synthesis of Polymers | PNKP, MGAM, COASY | NR5A1 4095/4885TSHR 4699/4885PLA2G2A 3260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.