Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10126871 | 0.79 | MAPT (0.54) | MAPTGAAMEN1KMT2APOLB | |
| SCHEMBL20684214 | 0.78 | MAPT (0.52) | MAPTGAAMEN1KMT2APOLB | |
| SCHEMBL855240 | 0.74 | MAPT (0.58) | MAPTGAAMEN1KMT2APOLB | |
| SCHEMBL28904897 | 0.73 | MAPT (0.42) | MAPTGAAMEN1KMT2APOLB | |
| SCHEMBL6698866 | 0.71 | MAPT (0.54) | MAPTGAAMEN1KMT2APOLB | |
| SCHEMBL247849 | 0.71 | MAPT (0.67) | MAPTGAAMEN1KMT2APOLB | |
| SCHEMBL3757787 | 0.69 | GAA (0.49) | MAPTGAAMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL2863287 | 0.69 | MAPT (0.64) | MAPTGAAMEN1KMT2APOLB | |
| SCHEMBL1954189 | 0.69 | MAPT (0.64) | MAPTGAAMEN1KMT2APOLB | |
| SCHEMBL19373320 | 0.68 | MAPT (0.46) | MAPTGAAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455413-B2 | Additive for oils and lubricant comprising the same | KH NEOCHEM CO., LTD. (JP) | 2013-06-04 | — | — | US | disclosed |
| US-20100298183-A1 | ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME | KYOWA HAKKO CHEMICAL CO., LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298183-A1 | ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME | NCOA2, NCOR2, NR1H2 | MAPT 4173/4885GAA 4788/4885MEN1 3819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.