Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PLEC | Q15149 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13091135 | 0.75 | GAA (0.45) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL1248173 | 0.71 | TDP1 (0.44) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL21058261 | 0.70 | MAPT (0.50) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL3757783 | 0.69 | MAPT (0.50) | GAAMAPTPOLBMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL9364517 | 0.68 | MAPT (0.43) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL5983235 | 0.68 | NPC1 (0.48) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL19130783 | 0.66 | TSHR (0.48) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15478310 | 0.66 | TSHR (0.48) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL193237 | 0.64 | MAPT (0.39) | GAAMAPTPOLBNPSR1HTT | |
| SCHEMBL1199683 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455413-B2 | Additive for oils and lubricant comprising the same | KH NEOCHEM CO., LTD. (JP) | 2013-06-04 | — | — | US | disclosed |
| US-20100298183-A1 | ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME | KYOWA HAKKO CHEMICAL CO., LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298183-A1 | ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME | NCOA2, NCOR2, NR1H2 | GAA 4788/4885MAPT 4173/4885POLB 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.