Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | EEF2K | O00418 | 3/20 | 0.45 |
| ▸ | EEF2 | P13639 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442380 | 1.00 | KDM4E (0.54) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL398563 | 1.00 | KDM4E (0.54) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL399310 | 0.92 | KDM4E (0.52) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL10148123 | 0.90 | KDM4E (0.53) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL3759456 | 0.88 | KDM4E (0.43) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL399439 | 0.87 | KDM4E (0.57) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL398291 | 0.87 | KDM4E (0.57) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL10148288 | 0.87 | ATM (0.50) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL10148282 | 0.86 | GAA (0.52) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL3763230 | 0.86 | HPGD (0.42) | KDM4ETSHRALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311715-A1 | ALPHA CARBOLINES AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311715-A1 | ALPHA CARBOLINES AND USES THEREOF | CHRM1, CNR1, CXCR1 | KDM4E 2021/4885TSHR 1997/4885ALDH1A1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.