Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3759456 | 0.90 | KDM4E (0.43) | HPGDKDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL399696 | 0.88 | HPGD (0.42) | HPGDKDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL10148318 | 0.87 | HPGD (0.40) | HPGDKDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL398563 | 0.86 | KDM4E (0.54) | HPGDKDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL3757891 | 0.86 | KDM4E (0.54) | HPGDKDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL3442380 | 0.86 | KDM4E (0.54) | HPGDKDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL399931 | 0.84 | KDM4E (0.55) | HPGDKDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL396235 | 0.83 | HPGD (0.37) | HPGDKDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL14456914 | 0.82 | KDM4E (0.43) | HPGDKDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL399310 | 0.78 | KDM4E (0.52) | HPGDKDM4EALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311715-A1 | ALPHA CARBOLINES AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311715-A1 | ALPHA CARBOLINES AND USES THEREOF | CHRM1, CNR1, CXCR1 | HPGD 1661/4885KDM4E 2021/4885ALDH1A1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.