⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000892 | 0.78 | — | — | |
| SCHEMBL1381999 | 0.47 | — | — | |
| SCHEMBL347419 | 0.47 | — | — | |
| SCHEMBL56632 | 0.47 | — | — | |
| Aziridine SCHEMBL6424974 | 0.45 | — | — | |
| SCHEMBL363279 | 0.45 | — | — | |
| SCHEMBL17846158 | 0.42 | — | — | |
| Aziridine SCHEMBL2267 | 0.36 | — | — | |
| SCHEMBL27530 | 0.36 | — | — | |
| SCHEMBL1198563 | 0.36 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4548 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752497-B1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | claimed |
| US-20240115553-A1 | COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY | AZEVAN PHARMACEUTICALS, INC. (US) | 2024-04-11 | — | — | US | claimed |
| CN-117384167-A | Dihydropyrimidine [4,5-d ] pyrimidine-2 (H) -ketone Nrf2 activator and preparation method and application thereof | 寒武智元(南京)生物医药科技有限公司 | 2024-01-12 | — | — | CN | claimed |
| EP-4301816-A1 | COATING COMPOSITIONS COMPRISING A POLYSULFIDE CORROSION INHIBITOR | PRC-Desoto International, Inc. (US) | 2024-01-10 | — | — | EP | claimed |
| CN-117377727-A | Coating composition comprising polysulfide corrosion inhibitor | PRC-迪索托国际公司 | 2024-01-09 | — | — | CN | claimed |
| CN-112218857-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2023-11-21 | — | — | CN | claimed |
| CN-116327950-A | Use of a composition for the treatment of neuropsychiatric symptoms of neurodegenerative diseases | 阿泽范药品公司 | 2023-06-27 | — | — | CN | claimed |
| CN-116139282-A | Compositions and methods for treating neurodegenerative diseases | 阿泽范药品公司 | 2023-05-23 | — | — | CN | claimed |
| CN-106459021-B | Compositions and methods for treating neurodegenerative diseases | 阿泽范药品公司 | 2023-04-07 | — | — | CN | claimed |
| US-11584745-B2 | Aromatic heterocyclic compound, intermediate thereof, preparation method therefor, and pharmaceutical composition and use thereof | SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) | 2023-02-21 | — | — | US | claimed |
| US-6818772-B2 | DIETETICS, SLEEP DISORDERS, EATING DISORDERS, SEXUAL DISORDERS, CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | ABBOTT LABORATORIES | 2004-11-16 | — | — | US | claimed |
| US-20040121964-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBOTT LABORATORIES | 2004-06-24 | — | — | US | claimed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | claimed |
| US-6627626-B2 | Antiinflammation agents and antiarthritic agents colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals. | PFIZER INC. | 2003-09-30 | — | — | US | claimed |
| US-20030144279-A1 | 5-Heterocyclo-pyrazoles | MINICH MARTHA L (US) | 2003-07-31 | — | — | US | claimed |
| WO-2003037352-A1 | 1-PHENYL-5-N-HETEROCYCLYL-PYRAZOLES AS CYCLOOXYGENASE INHIBITORS FOR THE TREATMENT OF INFLAMMATION ASSOCIATED DISORDERS | PFIZER PRODUCTS INC. (US) | 2003-05-08 | — | — | WO | claimed |
| EP-1308161-A1 | 5-N-heterocyclyl-1-(4-sulfonyl-phenyl)-1H-pyrazole derivatives with cyclooxygenase 2 (COX-2) inhibiting activity for the treatment of inflammatory diseases | Pfizer Products Inc. (US) | 2003-05-07 | — | — | EP | claimed |
| EP-0394991-B1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-08-17 | — | — | EP | claimed |
| US-5102877-A | Carbapenicillin antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | claimed |
| EP-0394991-A1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | claimed |