⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL27093448 | 0.95 | — | — | |
| SCHEMBL1615244 | 0.87 | HIF1A (0.39) | — | |
| Thiomorpholine SCHEMBL27610943 | 0.87 | HIF1A (0.39) | — | |
| SCHEMBL15668579 | 0.87 | HIF1A (0.39) | — | |
| SCHEMBL19621386 | 0.87 | HIF1A (0.39) | — | |
| SCHEMBL9994097 | 0.87 | HIF1A (0.39) | — | |
| Thiomorpholine SCHEMBL2273 | 0.80 | — | — | |
| SCHEMBL9873225 | 0.80 | HIF1A (0.42) | — | |
| Thiomorpholine SCHEMBL145846 | 0.80 | — | — | |
| Thiomorpholine SCHEMBL93637 | 0.80 | HIF1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240181685-A1 | PROCESS FOR CONTINUOUS PRODUCTION OF FOAMS USING AN AUXILIARY INLINE MIXER | EVONIK OPERATIONS GMBH (DE) | 2024-06-06 | — | — | US | claimed |
| EP-4314157-A1 | PROCESS FOR CONTINUOUS PRODUCTION OF FOAMS USING AN AUXILIARY INLINE MIXER | Evonik Operations GmbH (DE) | 2024-02-07 | — | — | EP | claimed |
| US-20200207938-A1 | USE OF POLYOLETHERS FOR PRODUCING POROUS PLASTIC COATINGS | EVONIK OPERATIONS GMBH (DE) | 2020-07-02 | — | — | US | claimed |
| EP-3071570-A1 | 2,6-SUBSTITUTED PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | Pfizer Inc. (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015075598-A1 | 2,6-SUBSTITUTED PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | PFIZER INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| US-20050040109-A1 | Method of separation of small molecules from aqueous solutions | U.S. DEPARTMENT OF ENERGY | 2005-02-24 | — | — | US | disclosed |