Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892589 | 0.86 | MGLL (0.60) | MGLLTP53MAPTNPC1ALDH1A1 | |
| SCHEMBL2293225 | 0.86 | MGLL (0.60) | MGLLTP53MAPTNPC1ALDH1A1 | |
| SCHEMBL3752705 | 0.85 | MGLL (0.51) | MGLLTP53MAPTNPC1ALDH1A1 | |
| SCHEMBL8748204 | 0.85 | MGLL (0.59) | MGLLTP53MAPTNPC1ALDH1A1 | |
| SCHEMBL2088984 | 0.85 | MGLL (0.59) | MGLLTP53MAPTNPC1ALDH1A1 | |
| SCHEMBL30853659 | 0.85 | MGLL (0.59) | MGLLTP53MAPTNPC1ALDH1A1 | |
| SCHEMBL17653814 | 0.85 | MGLL (0.59) | MGLLTP53MAPTNPC1ALDH1A1 | |
| SCHEMBL591401 | 0.85 | MGLL (0.59) | MGLLTP53MAPTNPC1ALDH1A1 | |
| SCHEMBL24890912 | 0.84 | KDM1A (0.47) | MGLLTP53MAPTNPC1ALDH1A1 | |
| SCHEMBL705457 | 0.84 | MGLL (0.58) | MGLLTP53MAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566392-B | A kind of preparation method of bacterio protein synthetic inhibitor | 正大天晴药业集团股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105503955-B | A kind of preparation method of the compound of resisting gram-positive bacteria | 正大天晴药业集团股份有限公司 | 2018-11-20 | — | — | CN | disclosed |
| CN-105418678-B | A kind of preparation method of Tedizolid Phosphate | 正大天晴药业集团股份有限公司 | 2018-11-20 | — | — | CN | disclosed |
| CN-105837633-B | A kind of preparation method of antimicrobial compound | 正大天晴药业集团股份有限公司 | 2018-11-20 | — | — | CN | disclosed |
| CN-107722056-A | The preparation method of Tedizolid Phosphate | 重庆华邦胜凯制药有限公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-105837633-A | Preparation method of antimicrobial compound | 正大天晴药业集团股份有限公司 | 2016-08-10 | — | — | CN | disclosed |
| US-20100298384-A1 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-11-25 | — | — | US | disclosed |
| US-20100298384-A1 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-11-25 | — | — | US | disclosed |
| WO-2008143649-A2 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008143649-A2 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298384-A1 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | OXA1L, MIF, VIP | MGLL 1065/4885TP53 3525/4885MAPT 3957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.