Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30505205 | 0.75 | STAT3 (0.41) | CDK2STAT3ATG4BNPC1MEN1 | |
| SCHEMBL29057000 | 0.75 | STAT3 (0.41) | CDK2STAT3ATG4BNPC1MEN1 | |
| SCHEMBL29056976 | 0.73 | NPC1 (0.46) | CDC7CDK2STAT3ATG4BNPC1 | |
| SCHEMBL27801967 | 0.72 | NPC1 (0.48) | CDC7CDK2STAT3ATG4BNPC1 | |
| SCHEMBL375846 | 0.71 | LMNA (0.57) | STAT3ATG4BNPC1MEN1RAB9A | |
| SCHEMBL30505182 | 0.68 | NPC1 (0.41) | EIF4ESCN9ASTAT3ATG4BNPC1 | |
| SCHEMBL29057035 | 0.68 | NPC1 (0.41) | EIF4ESCN9ASTAT3ATG4BNPC1 | |
| SCHEMBL30505239 | 0.68 | MAPT (0.43) | CDK2STAT3ATG4BNPC1MEN1 | |
| SCHEMBL29056977 | 0.68 | MAPT (0.43) | CDK2STAT3ATG4BNPC1MEN1 | |
| SCHEMBL21065546 | 0.68 | SCD (0.47) | SCN9ACDC7CCNE1CDK2DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408770-A2 | BROAD SPECTRUM BENZOTHIOPHENE-NITROTHIAZOLIDE AND OTHER ANTIMICROBIALS | University Of Virginia Patent Foundation (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010107736-A2 | BROAD SPECTRUM BENZOTHIOPHENE-NITROTHIAZOLIDE AND OTHER ANTIMICROBIALS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2010-09-23 | — | — | WO | disclosed |