Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516088 | 0.98 | HPGD (0.34) | HPGDHTTSLC6A3EPHX1SMN1; SMN2 | |
| SCHEMBL8923859 | 0.93 | — | — | |
| Urea SCHEMBL28709977 | 0.88 | NOS2 (0.36) | HPGDHTTSMN1; SMN2MAPTKDM4E | |
| SCHEMBL8392646 | 0.81 | HPGD (0.34) | HPGDHTTSLC6A3EPHX1SMN1; SMN2 | |
| SCHEMBL8392642 | 0.81 | HPGD (0.34) | HPGDHTTSLC6A3EPHX1SMN1; SMN2 | |
| SCHEMBL4502935 | 0.79 | HDAC8 (0.43) | HPGDHTTEPHX1SMN1; SMN2MAPT | |
| SCHEMBL12605720 | 0.78 | HPGD (0.36) | HPGDHTTSLC6A3EPHX1SMN1; SMN2 | |
| SCHEMBL15530058 | 0.78 | EPHX1 (0.34) | HPGDHTTEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL31680286 | 0.78 | HPGD (0.36) | HPGDHTTEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL12377981 | 0.76 | SMN1; SMN2 (0.38) | HPGDHTTEPHX1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023222115-A1 | HYDROXYAMIDE DERIVATIVE AND USE THEREOF | 四川汇宇制药股份有限公司 | 2023-11-23 | — | — | WO | disclosed |
| WO-2010138889-A1 | PEPTIDES FOR THE TREATMENT OF HCV INFECTIONS | CONCERT PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |