⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23213570 | 0.76 | — | — | |
| SCHEMBL27692261 | 0.69 | — | — | |
| SCHEMBL541690 | 0.69 | — | — | |
| SCHEMBL8833049 | 0.69 | — | — | |
| SCHEMBL9052049 | 0.69 | — | — | |
| SCHEMBL2005634 | 0.69 | — | — | |
| SCHEMBL3770920 | 0.69 | — | — | |
| SCHEMBL6746703 | 0.68 | NOS1 (0.37) | — | |
| SCHEMBL4666644 | 0.67 | APP (0.42) | — | |
| SCHEMBL27454091 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324977-B1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2022-07-13 | — | — | EP | disclosed |
| US-10556844-B2 | Pyrazole compounds as nitrification inhibitors | BASF SE (DE) | 2020-02-11 | — | — | US | disclosed |
| US-20180016199-A1 | PYRAZOLE COMPOUNDS AS NITRIFICATION INHIBITORS | BASF SCHWEIZ AG (CH) | 2018-01-18 | — | — | US | disclosed |
| WO-2016124769-A1 | PYRAZOLE COMPOUNDS AS NITRIFICATION INHIBITORS | BASF SE (DE) | 2016-08-11 | — | — | WO | disclosed |
| EP-2029570-B1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2014-10-15 | — | — | EP | disclosed |
| US-8324204-B2 | Fused thiophene derivatives as kinase inhibitors | UCB PHARMA SA (BE) | 2012-12-04 | — | — | US | disclosed |
| US-20100305066-A1 | Fused Thiophene Derivatives as Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2010-12-02 | — | — | US | disclosed |
| WO-2009122148-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS PI3K KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009071890-A1 | TRICYCLIC KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009071895-A1 | FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | disclosed |
| EP-2029570-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007141504-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2007-12-13 | — | — | WO | disclosed |
| EP-0918756-A1 | PARASITICIDAL PYRAZOLES | Pfizer Limited (GB) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004530-A1 | PARASITICIDAL PYRAZOLES | PFIZER LIMITED (GB) | 1998-02-05 | — | — | WO | disclosed |