Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22897641 | 0.84 | ALDH1A1 (0.54) | ALDH1A1CYP1A2HSD17B10TSHRTDP1 | |
| SCHEMBL29559837 | 0.84 | ALDH1A1 (0.54) | ALDH1A1CYP1A2HSD17B10TSHRTDP1 | |
| SCHEMBL15682757 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HSD17B10TSHRTDP1 | |
| SCHEMBL19514756 | 0.81 | ALDH1A1 (0.55) | ALDH1A1CYP1A2HSD17B10TSHRTDP1 | |
| SCHEMBL16687493 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP1A2HSD17B10TSHRTDP1 | |
| SCHEMBL16284318 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP1A2HSD17B10TSHRTDP1 | |
| SCHEMBL254406 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP1A2HSD17B10TSHRTDP1 | |
| SCHEMBL30800630 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP1A2HSD17B10TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL2890849 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP1A2HSD17B10TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL20521483 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP1A2HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771069-B1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | BAYER CROPSCIENCE AG (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-20080058389-A1 | Carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
| EP-1771069-A1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2005074686-A1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058389-A1 | Carboxamides | CBR3, CBR1, H1-10 | ALDH1A1 1944/4885CYP1A2 1998/4885HSD17B10 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.