SCHEMBL3759608

SCHEMBL3759608

CO/N=C(/C(=O)OC)c1ccccc1COc1cccc(C=C(Br)Br)c1

nearest known ligand 0.76

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.76
SPHK2 Q9NRA0 4/20 0.41
SPHK1 Q9NYA1 3/20 0.41
CCNB2 O95067 1/20 0.39
CDK1 P06493 1/20 0.39
CDK4 P11802 1/20 0.39
CCNB1 P14635 1/20 0.39
CCND1 P24385 1/20 0.39
CCNB3 Q8WWL7 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3754149 0.92 HIF1A (0.74) HIF1ASPHK2SPHK1CCNB2CDK1
SCHEMBL3749493 0.91 HIF1A (0.78) HIF1ASPHK2SPHK1CCNB2CDK1
SCHEMBL3747038 0.90 HIF1A (0.62) HIF1ASPHK2SPHK1CCNB2CDK1
SCHEMBL3747045 0.90 HIF1A (0.62) HIF1ASPHK2SPHK1CCNB2CDK1
SCHEMBL3752978 0.89 HIF1A (0.63) HIF1ASPHK2SPHK1NPC1RAB9A
SCHEMBL3759710 0.88 HIF1A (0.74) HIF1ASPHK2SPHK1CCNB2CDK1
SCHEMBL3686962 0.84 HIF1A (0.63) HIF1ANPC1RAB9A
SCHEMBL3683349 0.84 HIF1A (0.77) HIF1ANPC1RAB9ALMNAMAPK1
SCHEMBL3687120 0.84 HIF1A (0.63) HIF1ANPC1RAB9A
SCHEMBL22414343 0.84 HIF1A (1.00) HIF1ASPHK2SPHK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HIF1A 3994/4885SPHK2 3931/4885SPHK1 3932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.