SCHEMBL3752978

SCHEMBL3752978

CO/N=C(/C(=O)OC)c1ccccc1COc1ccc(C=C(Br)Br)cc1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.63
NR1H4 Q96RI1 1/20 0.41
KDM4E B2RXH2 2/20 0.40
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
MAPT P10636 1/20 0.39
SPHK2 Q9NRA0 1/20 0.38
SPHK1 Q9NYA1 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
CAPN1 P07384 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3751694 0.92 HIF1A (0.61) HIF1ANR1H4KDM4EKMT2AMEN1
SCHEMBL3759552 0.89 HIF1A (0.50) HIF1ANR1H4KDM4EKMT2AMEN1
SCHEMBL3759546 0.89 HIF1A (0.50) HIF1ANR1H4KDM4EKMT2AMEN1
SCHEMBL3758377 0.89 HIF1A (0.63) HIF1ANR1H4KDM4EKMT2AMEN1
SCHEMBL3755605 0.89 HIF1A (0.66) HIF1ANR1H4KDM4EKMT2AMEN1
SCHEMBL3759608 0.89 HIF1A (0.76) HIF1ASPHK2SPHK1NPC1RAB9A
SCHEMBL3755404 0.87 HIF1A (0.61) HIF1ANR1H4KDM4EKMT2AMEN1
SCHEMBL6571845 0.85 HIF1A (0.80) HIF1AKDM4ECAPN1
SCHEMBL9025823 0.85 HIF1A (0.80) HIF1AKDM4ECAPN1
SCHEMBL3687120 0.85 HIF1A (0.63) HIF1AKMT2AMEN1MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HIF1A 3994/4885NR1H4 3791/4885KDM4E 143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.